TORCH检测在孕前优生健康检查中的临床应用及意义

Clinical Application and Significance of TORCH Detection in Pre-pregnancy Eugenics Health Examination

目的:分析TORCH检测在孕前优生健康检查中的临床应用及意义。方法:选取2018年3月-2019年4月于笔者所在医院进行孕前优生健康检查的育龄女性500例为研究对象,采用化学发光免疫分析(CLIA)技术对TORCH特异性IgM抗体和IgG抗体进行定量检测。结果:弓形虫IgM抗体、风疹病毒IgM抗体、巨细胞病毒IgM抗体、单纯疱疹病毒Ⅰ+Ⅱ型IgM抗体阳性率分别为1.0%、1.8%、3.0%、16.2%;弓形虫IgG抗体、风疹病毒IgG抗体、巨细胞病毒IgG抗体、单纯疱疹病毒Ⅰ+Ⅱ型IgG抗体阳性率分别为6.8%、18.0%、17.6%、16.0%。结论:采用化学发光免疫分析技术对孕前TORCH特异性抗体进行检测,可避免备孕女性于急性感染期妊娠,对提高优生水平具有重要作用,值得临床推广应用。

Objective: To analyze the clinical application and significance of TORCH detection in pre-pregnancy eugenics health examination. Method: Women of childbearing age who underwent pre-pregnancy eugenics health examination in our hospital from March 2018 to April 2019 were selected as subjects. Quantitative detection of TORCH-specific IgM antibodies and IgG antibodies was performed by chemiluminescence immunoassay(CLIA). Result: The positive rates of toxoplasma gondii IgM antibody, rubella virus IgM antibody, cytomegalo virus IgM antibody, and herpes simplex virus Ⅰ+Ⅱ type IgM antibody were 1.0%, 1.8%, 3.0% and 16.2%, respectively. The positive rates of toxoplasma gondii IgG antibody, rubella virus IgG antibody, cytomegalo virus IgG antibody, and herpes simplex virus Ⅰ+Ⅱ type IgG antibody were 6.8%, 18.0%, 17.6%, 16.0%, respectively. Conclusion: Chemoluminescence immunoassay technology is used to detect prepregnancy TORCH-specific antibodies, which can avoid pregnant women from conceiving during acute infectious period and play an important role in improving the level of eugenics. It is worthy of clinical promotion and application.