儿童鼻咽癌的治疗进展

Progress in the Treatment of Nasopharyngeal Carcinoma in Children

儿童鼻咽癌在儿童恶性肿瘤中占比1%~2%,发病率较低,以遗传易感性为主要发病特征。在初诊时,多数患儿实施放化疗综合治疗,但由于儿童生长发育尚不成熟,机体处于新陈代谢旺盛阶段,组织器官敏感性较高,正常组织耐受剂量较低,使得儿童更易出现放射性损伤。目前我国在儿童鼻咽癌治疗中,对于其的研究较少,故本次研究针对儿童鼻咽癌治疗措施、疗效、并发症等展开综述,为临床探索更多、更好的治疗途径,为鼻咽癌患儿谋取更多的福音。

Nasopharyngeal carcinoma in children account for 1%-2% of the malignant tumors in children, and the incidence rate is low, with genetic susceptibility as the main feature. At the initial diagnosis, most of the children were treated with radiotherapy and chemotherapy. However, due to the immature growth and development of children, the body is in the stage of metabolic hyperplasia, the sensitivity of tissues and organs is high, and the normal tissue tolerated dose is low, making children more susceptible to radiation injury. At present, there are few studies on the treatment of nasopharyngeal carcinoma in children in China. Therefore, this study reviews the treatment measures, curative effects and complications of nasopharyngeal carcinoma in children, so as to explore more and better treatment approaches for clinical practice and seek more benefits for children with nasopharyngeal carcinoma.