井穴刺络放血治疗急性中枢神经损伤的研究进展

Research advances in the clinical effect of bloodletting puncture at well-points in treatment of acute central nervous injury

十二井穴刺络放血疗法是中医传统的急救特色疗法。本文综述近30年此疗法在急性中枢神经损伤中的临床研究和机制研究,发现其能有效改善中风、颅脑外伤及一氧化碳中毒等引起的意识障碍、神经功能缺损及脑水肿,其作用机制与改善脑血流和组织供氧,修复血脑屏障,调节局部离子平衡等有关,今后应进一步开展设计严密的临床研究和系统深入的机制研究,以期更好地推广和指导临床应用。

Bloodletting puncture at twelve well-points is a characteristic emergency therapy in traditional Chinese medicine. This article reviewed the research advances in the clinical effect of this therapy in the treatment of acute central nervous injury and its mechanism of action over the past 30 years,and it is found that this therapy can effectively improve disturbance of consciousness,neurological defects,and cerebral edema caused by stroke,traumatic brain injury,and carbon monoxide poisoning. The mechanism involves the improvement of cerebral blood flow and tissue oxygen supply,repair of the blood-brain barrier,and regulation of local ion balance. Well-designed clinical trials and in-depth research on biological mechanisms should be performed in future to promote and guide its clinical application.