肠道菌群与慢性阻塞性肺疾病关系的中西医研究进展

Research progress of Chinese and western medicine on relationship between gut microflora and chronic obstructive pulmonary disease

随着肠道菌群研究的不断深入,其与肠外各系统、组织、器官的功能及病变之间的关联也受到广泛关注。慢性阻塞性肺疾病(COPD)作为全球范围内流行的高致死率、致残率的疾病,其发病机制至今尚未明确。文章就肠道菌群与COPD之间的关系作一综述,研究肠道菌群对COPD发生发展的影响,并从中医"肺与大肠相表里"、整体观念下的"邪正观"等理论视角认识两者的关系,以期为进一步研究肠道菌群及COPD的诊疗提供思路。

Nowadays, relationship between gut microfilora and functions and pathological changes of various systems, tissues and organs outside the intestine has attracted wide attention with the continuous deeply research on intestinal flora. As a worldwide epidemic disease, chronic obstructive pulmonary disease(COPD) has high rate of mortality and disability but its pathogenesis has not yet been clarified. This article reviewed the relationship between intestinal flora and COPD, in order to study the influence of intestinal flora on the occurrence and development of COPD, and understand it from the perspective of Chinese medicine theory. We wish to provide more approaches for diagnosis and treatment of COPD.