祛风胜湿方治疗大肠湿热型溃疡性结肠炎的疗效观察

Observation on effects of Qufeng Shengshi Decoction in the treatment of large intestinal dump-heat syndrome of ulcerative colitis

目的:观察祛风胜湿方治疗大肠湿热型溃疡性结肠炎(UC)的疗效。方法:共纳入104例大肠湿热型UC患者,随机分成观察组(54例)和对照组(50例)。观察组给予祛风胜湿方免煎颗粒,治疗组给予美沙拉嗪缓释颗粒(艾迪莎)。治疗4周后评价疗效。结果:治疗后两组主要症状评分、Geboes指数和Mayo活动指数均较本组治疗前显著改善(P<0.01,P<0.05),且治疗后观察组改善程度优于对照组(P<0.05)。结论:祛风胜湿方与美沙拉嗪缓释颗粒均可有效改善大肠湿热型UC患者临床症状、促进黏膜愈合、降低疾病活动指数,且祛风胜湿方疗效较佳。

Objective:To investigate the effects of Qufeng Shengshi Decoction in the treatment of large intestinal dumpheat syndrome of ulcerative colitis(UC).Methods:A total of 104 UC patients were randomly divided into observation group(54 cases)and control group(50 cases).The observation group was treated with Qufeng Shengshi Decoction and the control group was treated with Mesalazine Sustained Release Granules.The clinical effects were evaluated after four weeks of treatment.Results:After treatment,the main symptom scores,Geboes index and Mayo activity index of the two groups were significantly improved(P<0.01,P<0.05),the improvement degree of the observation group was better than that of the control group,and the difference was statistically significant(P<0.05).Conclusion:Both Qufeng Shengshi Decoction and Mesalazine Sustained Release Granules can effectively improve the clinical symptoms of large intestinal dump-heat syndrome of UC patients,promote mucosal healing,reduce disease activity index,and the efficacy of Qufeng Shengshi Decoction was better.