应用T2 mapping诊断关节软骨疾病研究进展

Research progress of using T2 mapping to diagnose articular cartilage diseases

关节软骨是关节的重要结构之一,在运动时传递机械应力,减少关节面间的摩擦力。软骨组织受损后很难自愈,因此早期诊断和治疗对其预后非常重要。T2 mapping是一种通过描述组织横向磁化衰减来反映组织特性的半定量分析的磁共振诊断技术,能较好地评价关节软骨的早期改变,具有很大的临床应用潜力。本文就T2-mapping的发展近况进行综述。

Articular cartilage is one of the most important articulates,which plays an role in transferring the mechanical stress when exercising and decreasing friction between joint surfaces.Due to the lack of blood supply for articular tissue,injuries after articulate damage are difficult for self-healing.Thus,early diagnosis and treatment are necessary for articular damages.As a noninvasive diagnosis method in videography,nuclear magnetic resonance(NMR)is of vital importance in diagnosing articular injuries.T2-mapping enables the evaluation of early change of the articular cartilage by describing the transverse magnetization attenuation to reflect the semi-quantitative analysis of tissue character and has clinical potentials.This article was aimed to review the recent development of T2-mapping in diagnosis of articular cartilage diseases.