糖尿病继发肺结核患者临床血糖控制及抗结核效果与影响因素分析

Studying on the clinical blood glucose control and the effect of anti-tuberculosis and its influencing factors in patients with diabetes secondary to pulmonary tuberculosis

目的:探讨糖尿病继发肺结核患者临床血糖控制及抗结核效果及影响因素。方法:2014年3月-2019年3月收治糖尿病继发肺结核患者160例,随机分为两组各80例。两组患者均采用抗结核治疗,在此基础上对照组单纯应用药物治疗,观察组采用胰岛素治疗。比较两组治疗后临床疗效及干预后血糖水平,分析疾病影响因素。结果:观察组治疗总有效率明显高于对照组,差异有统计学意义(P<0.05)。从治疗有效和无效患者的基本指标进行统计,两组病程、吸烟史、年龄等比较,差异有统计学意义(P<0.05),可将其作为糖尿病继发肺结核治疗效果的主要影响因素。观察组干预后血糖水平优于对照组,差异有统计学意义(P<0.05)。结论:糖尿病继发肺结核患者在治疗时,需要给予积极的血糖控制与抗结核治疗,同时结合患者病程、年龄、吸烟状况等制定治疗方案,优化治疗效果。

Objective:To study the clinical blood glucose control and the effect of anti-tuberculosis and its influencing factors in patients with diabetes secondary to pulmonary tuberculosis.Methods:From Mar 2014 to Mar 2019,160 cases of pulmonary tuberculosis secondary with diabetes mellitus were selected,80 cases were randomly divided into two groups.The anti-tuberculosis treatment was used,on this basis,the control group was treated with simple drugs;the observation group was treated with insulin.The total effective rate of treatment and the level of blood glucose after intervention were compared between the two groups,and the influencing factors of disease were discussed.Results:The total effective rate of treatment in the observation group was significantly higher than the control group,the difference is statistically significant(P<0.05);Statistics from basic indicators for the treatment of effective and ineffective patients,with comparison of course of disease,smoking history,age and so on,the difference was statistically significant(P<0.05),it can be regarded as the main influencing factor of the therapeutic effect of pulmonary tuberculosis secondary to diabetes mellitus.The level of blood glucose in the observation group was better than the control group after intervention.Conclusion:Patients with pulmonary tuberculosis secondary to diabetes should be treated with active blood glucose control and anti-tuberculosis treatment,at the same time,the treatment plan was developed in combination with the course,age and smoking status of the patient,and the treatment effect was optimized.