根管消毒药物对年轻恒牙牙髓血运重建术疗效影响的临床研究

Clinical Study on the Effect of Root Canal Disinfection on the Treatment of Young Permanent Teeth Pulp Revascularization

目的观察分析根管消毒药物对年轻恒牙牙髓血运重建术的疗效影响。方法选取该院2017年1月—2018年2月收治的90例因牙髓病变或者根尖周感染的年轻恒牙患者(总共132颗患牙),所有患者均进行牙髓血运重建术,按照随机双盲实验方法分为实验组(45例66颗患牙,应用甲硝唑、米诺环素和环丙沙星治疗方法)和对照组(45例66颗患牙,应用氢氧化钙治疗方法)。采用统计学分析两组年轻恒牙患者的临床治疗成功率、平均愈合时间。结果实验组中有30例男患儿、15例女患儿;平均年龄为(12.28±3.34)岁;患牙类型:27例上颌切牙、18例上颌前磨牙、21例下颌前磨牙。对照组中有27例男患儿、18例女患儿;平均年龄为(12.37±3.05)岁;患牙类型:30例上颌切牙、18例上颌前磨牙、18例下颌前磨牙。实验组年轻恒牙患者的临床治疗成功率显著高于对照组(χ^2=6.545,P=0.003),实验组年轻恒牙患者的平均愈合时间短于对照组(t=10.526,P=0.000)。结论甲硝唑、米诺环素和环丙沙星治疗方法相比起氢氧化钙治疗方法可使得对年轻恒牙牙髓血运重建术的疗效更为显著。

Objective To observe the effect of root canal disinfection on the revascularization of young permanent teeth.Methods A total of 90 young permanent patients(132 teeth)with endodontic infection or periapical infection were enrolled in our hospital from January 2017 to February 2018.All patients underwent pulp blood.According to the randomized double-blind experiment,the patients were divided into experimental group(45 cases of 66 teeth,treatment with metronidazole,minocycline and ciprofloxacin)and control group(45 cases of 66 teeth,with calcium hydroxide treatment).The clinical success rate and average healing time of two groups of young permanent teeth patients were analyzed statistically.Results There were 30 male patients and 15 female patients in the experimental group;the mean age was(12.28±3.34)years old;the type of teeth:27 cases of maxillary incisors,18 cases of maxillary premolars,and 21 cases of mandibular premolars.There were 27 male patients and 18 female patients in the control group;the average age was(12.37±3.05)years old;the type of teeth:30 cases of maxillary incisors,18 cases of maxillary premolars,and 18 cases of mandibular premolars.The clinical success rate of the young permanent teeth in the experimental group was significantly higher than that in the control group(χ^2=6.545,P=0.003).The average healing time of the young permanent teeth in the experimental group was shorter than that of the control group(t=10.526,P=0.000).Conclusion Metronidazole,minocycline,and ciprofloxacin are more effective than calcium hydroxide in the treatment of young permanent teeth.