米非司酮联合甲氨蝶呤治疗异位妊娠与腹腔镜下手术治疗异位妊娠疗效分析

Therapeutic Effect of Mifepristone Combined with Methotrexate on Ectopic Pregnancy and Laparoscopic Surgery for Ectopic Pregnancy

目的研究米非司酮联合甲氨蝶呤的药物疗法、腹腔镜下手术对于异位妊娠的治疗效果分析。方法随机将2015年1月-2018年12月在该院住院治疗80例异位妊娠患者分为两组,药物(治疗)组接受米非司酮联合甲氨蝶呤的药物保守治疗,手术组接受腹腔镜下手术治疗,比较两组治疗效果。结果手术组异位妊娠治疗成功率为100.00%,药物组成功率90.00%(χ~2=4.210,P<0.05),手术组住院时间及治疗成功率优于药物组(P<0.05);手术组患者在治疗后1周血β-HCG水平低于药物组,β-HCG水平恢复正常时间短于药物组(P<0.05);并发症发生率低。结论腹腔镜下手术治疗异位妊娠的效果优于米非司酮联合甲氨蝶呤的药物治疗,治疗成功率高,恢复快,并发症少。缩短患者住院时间,减轻患者医疗负担。

Objective To study the drug therapy of mifepristone combined with methotrexate and analyze the therapeutic effect of laparo-scopic surgery on ectopic pregnancy. Methods 80 patients with ectopic pregnancy in the hospital from January 2015 to December2018 were randomly divided into two groups. The drug(treatment) group was treated with mifepristone combined with methotrexate conservative treatment, and the operation group was treated with laparoscopic surgery. The therapeutic effects of the two groups were compared. Results The success rate of ectopic pregnancy in the operation group was 100.00%, and the drug composition power was90.00%(χ~2=4.210, P<0.05). The hospitalization time and treatment in the operation group were successful(P<0.05). The serum β-HCG level in the operation group was lower than that in the drug group one week after treatment, and the recovery time of β-HCG level was shorter than that in the drug group(P<0.05), and the incidence of complications was lower in the operation group than in the drug group. Conclusion Laparoscopic surgery is better than mifepristone combined with methotrexate in the treatment of ectopic preg-nancy. Shorten the hospitalization time of patients and reduce the medical burden of patients.