阿托伐他汀+曲美他嗪治疗冠心病心绞痛效果

Effect of Atorvastatin + Trimetazidine on Angina Pectoris

目的研究阿托伐他汀+曲美他嗪治疗冠心病心绞痛的效果。方法本次将2018年4月-2019年3月期间本院收治110例冠心病心绞痛患者按照随机数字表法分为两组,在常规治疗的基础上,对照组55例采用阿托他汀治疗,观察组55例采用阿托伐他汀+曲美他嗪治疗。将两组的临床相关指标进行比对。结果观察组患者治疗后的心绞痛发作次数(3.05±1.17)次/周,少于对照组,持续时间(3.09±1.34)min/次,短于对照组,差异均具有统计学意义(t=8.412、14.685,P<0.05);观察组的临床总有效率(96.36%)高于对照组,差异具有统计学意义(χ^2=4.950,P<0.05);两组的不良反应发生率进行比较,差异无统计学意义(P>0.05)。结论曲美他嗪与阿托伐他汀联合应用在冠心病心绞痛患者的治疗中安全有效,有助于心绞痛症状的改善。

Objective To study the effect of atorvastatin+trimetazidine on coronary heart disease with angina pectoris. Methods From April 2018 to March 2019, 110 patients with coronary heart disease and angina pectoris were divided into two groups according to the random number table. Onthe basis of routine treatment,55 patients in the control group were treated with atorvastatin. 55 patients in the observation group were treated with atorvastatin+trimetazidine.The clinically relevant indicators of the two groups were compared. Rseults The number of angina attacks(3.05±1.17) beats/week in the observation group was lower than that in the control group, and the duration(3.09±1.34) min/time was shorter than that of the control group. The difference was statistically significant(t = 8.412, 14.685, P<0.05). The total clinical effective rate of the observation group(96.36%) was higher than that of the control group,and the difference was statistically significant( χ^2 = 4.950, P<0.05). The incidence of adverse reactions was compared between the two groups.Academic significance(P>0.05). Conclusion The combination of trimetazidine and atorvastatin is safe and effective in the treatment of patients with angina pectoris and contributes to the improvement of angina pectoris.