新辅助动脉化疗在宫颈癌中的临床应用

Clinical Application of Neoadjuvant Arterial Chemotherapy in Cervical Cancer

目的:探究在宫颈癌患者中采用新辅助动脉化疗治疗的效果。方法:将笔者所在医院妇科2018年2月-2019年2月收治的80例宫颈癌患者作为研究对象,实施传统手术治疗的40例作为对照组,实施传统手术联合新辅助动脉化疗法治疗的40例为研究组。对比两组治疗效果、术后病理检查情况及并发症发生率。结果:研究组治疗总有效率明显高于对照组,术后病理检查中间质浸润≥50%、淋巴结转移及脉管癌栓发生率均低于对照组,且术后盆腔剧烈疼痛、延迟性疼痛及发热发生率低于对照组,差异均有统计学意义(P<0.05)。结论:在宫颈癌患者治疗中实施新辅助动脉化疗能够有效提升治疗效果,改善患者术后病理异常情况,降低术后并发症发生率,值得推广应用。

Objective: To investigate the effect of neoadjuvant arterial chemotherapy in patients with cervical cancer. Method: A total of 80 cases of cervical cancer patients admitted to the department of gynecology of the author’s hospital from February 2018 to February 2019 were selected as the research object. The implementation of traditional surgery treatment of 40 patients as the control group, and the implementation of traditional surgery combined with neoadjuvant arterial chemotherapy treatment of 40 patients as the study group. Treatment effect, postoperative pathological examination and complication rate of the two groups were compared. Result: The total effective rate of treatment in the study group was significantly higher than that of the control group, and the incidences of mesenchymal infiltration≥50%, lymph node metastasis and vascular tumor emboli in the postoperative pathological examination were lower than those of the control group, and the incidence of severe pelvic pain, delayed pain and fever after surgery was lower than that of the control group, and the differences were statistically significant(P<0.05). Conclusion: The application of neoadjuvant arterial chemotherapy in the treatment of cervical cancer patients can effectively improve the therapeutic effect, improve the postoperative pathological abnormalities, and reduce the incidence of postoperative complications, which is worthy of popularization and application.