枸橼酸抗凝血液灌流在273例急性中毒患者急救中的应用

Citrate anticoagulation hemoperfusion in the treatment of 273 patients

急性中毒患者早期进行血液灌流可以快速有效的清除毒物,对改善患者预后起到重要作用。血液灌流治疗的关键是安全有效的抗凝,枸橼酸局部抗凝对患者全身凝血机制、内环境等影响小。我们于2018年10月,通过回顾性分析2013年12月至2017年12月山东第一医科大学第二附属医院急诊重症监护室收治的273例行枸橼酸抗凝血液灌流的中毒患者的临床资料和救治情况,分析枸橼酸抗凝血液灌流在急性中毒患者急救中的作用,旨在为中毒患者枸橼酸抗凝血液灌流提供一定的临床参考。

Early hemoperfusion in poisoned patients can remove poisons rapidly and effectively,which plays an important role in improving the prognosis of patients.The key of hemoperfusion therapy is the safe and effective anticoagulation.The local citrate anticoagulation effect acid is good,it also has little effect on the systemic coagulation mechanism and internal environment of patients,so it is worthy of promotion.We retrospectively analyzed the clinical data and treatment of 273 patients who were poisoned by citrate anticoagulant in the emergency intensive care unit of the Second Affiliated Hospital of Shandong First Medical University,aiming at perfusion of citrate anticoagulant in patients with poisoning.Provide a certain clinical reference.