CT导引下氩氦刀冷冻消融治疗原发性小肝癌的近期效果

Short-term Efficacy of Argon-helium Cryoablation under CT Guidance in the Treatment of Primary Small Liver Cancer

目的:探讨CT导引下氩氦刀冷冻消融治疗原发性小肝癌的近期效果及安全性。方法:回顾性分析笔者所在医院2014年9月-2018年8月经CT导引下氩氦刀冷冻消融靶向治疗原发性小肝癌患者18例,共19枚病灶(直径<3 cm)。术后1~2个月复查肿瘤标记物AFP及增强CT、MR,观察临床效果。结果:全部患者均穿刺成功。术后增强CT、MR复查显示,病灶完全灭活率为79%(15/19),病灶部分灭活率为21%(4/19);术后AFP转阴率为72%(13/18);两组均无大出血、肝破裂及死亡等严重并发症。结论:CT导引下氩氦刀冷冻消融治疗原发性小肝癌的近期效果确切,安全性好。

Objective:To evaluate the short-term efficacy and safety of argon-helium cryoablation under CT guidance in the treatment of primary small liver cancers.Method:Retrospective analysis of 18 patients with primary small liver cancer treated by argon-helium cryoablation under CT guidance from September 2014 to August 2018 in the author’s hospital,with a total of 19 lesions(diameter<3 cm).And 1 to 2 months after surgery,the tumor markers AFP and enhanced CT and MR were reexamined to observe the clinical effect.Result:Puncture was successful in all patients.Postoperative enhanced CT and MR reexamination showed that the complete inactivation rate of lesions was 79%(15/19),and the partial inactivation rate of lesions was 21%(4/19).Postoperative AFP negative conversion rate was 72%(13/18).There were no serious complications such as severe bleeding,liver rupture or death in both groups.Conclusion:The argon-helium cryoablation under CT guidance is effective and safe in the treatment of primary small liver cancer.