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抗VEGF药物治疗视网膜分支静脉阻塞黄斑水肿疗效观察 被引量:2

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摘要 目的研究抗血管内皮生长因子(VEGF)在视网膜分支静脉阻塞黄斑水肿治疗中的作用。方法选取2017年6月~2018年12月我院视网膜分支静脉阻塞黄斑水肿的病例32例,随机分成两组,研究组(n=16)给与VEGF联合视网膜激光光凝治疗,对照组(n=16)单纯给与视网膜激光光凝治疗,观察研究组和对照组治疗前后的最佳矫正视力(BCVA)、眼压(IOP)、黄斑中心凹厚度(CMT)、疗效、不良反应等。结果治疗后,研究组和对照组的BCVA较治疗前均明显提高,CMT较治疗前均明显缩小,眼压降低(P均<0.05);治疗12周后,研究组的BCVA高于对照组,CMT小于对照组,眼压低于对照组(P均<0.05)。治疗24周后研究组的总有效率高于对照组(P<0.05)。治疗期间,患者均未出现不良反应。结论抗VEGF药物在视网膜分支静脉阻塞黄斑水肿治疗中疗效显著,安全性较高。
出处 《海峡药学》 2019年第11期156-158,共3页 Strait Pharmaceutical Journal
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