摘要
Dear Editor,Gene editing is a process to introduce desired changes into targeted loci of genomic DNA.Recently,type II clustered regularly in terspaced short palindromic repeats-associated Cas9 endonuclease(CRISPR/Cas9)system has been demonstrated as a versatile tool for engineering eukaryote genome(Hsu et al.,2014),such as in mice(Zuo et al.,2017).
基金
The authors declare no Competing Financial or Non-Financial Interests.This work was supported by National Center for International Research(2017B01012)
National Natural Science Foundation of China(Grant Nos.31771299,81600380 and 31600958)
Natural Science Foundation of Jiangsu Proving(BK20160313,BK20160317).