断食与热量限制在肿瘤防治中的作用

Fasting and caloric restriction in cancer prevention and therapy

肿瘤是导致人口死亡的第二大病因。随着老龄化人口的增长,以及肥胖、吸烟和不良饮食习惯等风险因素的增加,肿瘤的发病率可能还将继续增长。目前肿瘤的预防和治疗措施仍然不能有效地控制肿瘤的发生和发展,急需探索新的肿瘤防治方法。近年来的研究发现,断食和热量限制对预防恶性肿瘤的发生和提高肿瘤治疗的效果有许多益处。因此,本文综述了断食和热量限制在肿瘤领域中近年来的研究进展,以期为肿瘤的预防和治疗提供一条新的思路。

Cancer is the second cause for human death. The incidence of cancer is increasing with the expansion of the elder population and the increase of risk factors such as smoking, obesity and unhealthy life style. The present interventions to prevent and treat cancers are largely ineffective,so the novel strategy for cancer prevention and therapy is needed.Recently, fasting and caloric restriction are found to be beneficial for cancer prevention and therapy. This review aims to summarize the major progresses of fasting and caloric restriction in cancer research,which will shed light on the cancer prevention and therapy.