摘要
帕金森病(PD)是常见神经退行性疾病,PET对早期鉴别、诊断和评价PD具有特别优势,主要示踪剂为反映葡萄糖代谢的18 F-FDG和反映纹状体多巴胺能神经元突触功能的靶向示踪剂。本文就18 F-FDG PET脑显像和多巴胺能神经元突触功能PET脑显像应用于PD研究现状和进展进行综述。
Parkinson disease(PD)is a common neurodegenerative disease.PET has special advantages in early identification,diagnosis and evaluation of PD.The main PET tracers contain 18 F-FDG and dopaminergic neuron function targeting imaging tracers.The research status and progresses of 18 F-FDG PET brain imaging and dopaminergic neuron function targeting imaging on evaluation of PD were reviewed in this article.
作者
宋天彬
卢洁
SONG Tianbin;LU Jie(Department of Nuclear Medicine,Xuanwu Hospital,Capital Medical University,Beijing 100053,China;Department of Radiology,Xuanwu Hospital,Capital Medical University,Beijing 100053,China;Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics,Beijing 100053,China)
出处
《中国医学影像技术》
CSCD
北大核心
2019年第12期1884-1888,共5页
Chinese Journal of Medical Imaging Technology
基金
国家自然科学基金面上项目(81671662)
北京市医管局人才培养计划“登峰”项目(DFL20180802)
