超声在诊断透析相关淀粉样变性中的研究进展

Progresses in ultrasound diagnosis of dialysis-related amyloidosis

透析相关淀粉样变性(DRA)是长期透析患者的严重并发症之一。DRA常引起骨关节系统的渐进性损害,严重影响患者的后续治疗及生活质量。当前,诊断DRA主要依靠患者的临床症状及体征,但对于病变部位的观察以及严重度的评估,仍然缺乏客观方法。影像学方法有助于DRA的筛查,其中超声成像技术对于大部分肌骨系统的显示非常敏感,且对于局部病变的评估具有一定优势。本文对超声成像技术在DRA诊断中的研究进展进行综述。

Dialysis-related amyloidosis(DRA)is one of the serious complications in long-term dialysis patients.DRA often causes progressive damage to the bone and joint system,which seriously affects the follow-up treatment and quality of life of the patients.At present,the diagnosis of DRA mainly depends on the clinical symptoms and signs of the patients,but there is still lack of objective methods for the observation of the location of the lesion and the assessment of the severity of the disease.The imaging method is helpful for DRA screening,in which ultrasound imaging is very sensitive to the display of most musculoskeletal systems and has a natural advantage in the evaluation of local lesions.The progresses of ultrasonic imaging technology in DRA diagnosis was reviewed in this paper.