期刊文献+

甲状腺功能减低症对妊娠早期流产的影响

原文传递
导出
摘要 目的探讨甲状腺功能减低症(甲减)对妊娠早期流产的影响。方法选择2017年1月~2018年6月期间于我院就诊的具有腹痛或阴道出血等先兆流产症状的116例早孕期产妇作为研究对象,均进行甲状腺功能检测,根据有无甲减情况分为观察组与对照组。观察组予以左甲状腺素钠片治疗,比较两组甲状腺功能指标[促甲状腺激素(TSH)、抗甲状腺过氧化酶抗体(TPOAb)、游离T3(FT3)、游离T4(FT4)及和抗甲状腺球蛋白抗体(TGAB)]与妊娠结局。结果两组FT4指标相比,差异无统计学意义(P>0.05);对照组TSH、FT3、TPOAb、TGAB等指标水平均明显低于观察组,差异有统计学意义(P<0.05);两组保胎成功率相比,差异无统计学意义(P>0.05)。结论甲减是妊娠早期流产的危险因素,孕早期进行甲状腺功能筛查、异常者接受治疗是降低产妇流产率的关键,具有非常重要的临床意义。
作者 常晓伟
出处 《首都食品与医药》 2019年第23期23-23,共1页 Capital Food Medicine
  • 相关文献

参考文献2

二级参考文献23

  • 1Sahu MT,Das V,Mittal S,et al.Overt and subclinical thyroid dysfunction among Indian pregnant women and its effect on maternal and fetal outcome[J].Arch Gynecol Obstet,2010,281(2):215-220.
  • 2Kim CH,Ahn JW,Kang SP,et al.Effect of levothyroxine treatment on in vitro fertilization and pregnancy outcome in infertile women with subclinical hypothyroidism under- going in vitro fertilization/intracytoplasmic sperm injec- tion[J].Fertil Steril,2011,95(5): 1650-1654.
  • 3Lazzarin N,Moretti C,De Felice G,et al.Further evidence on the role of thyroid autoimmunity in women with recur- rent miscarriage[J].Int J Endocrinol,2012,26(1):717185.
  • 4Pradhan M,Anand B,Singh N,et al,Thyroid peroxidase antibody in hypothyroidism:it's effect on pregnancy[J].J Matern Fetal Neonatal Med,2013,26(6):581-583.
  • 5Li Y,Shan Z,Teng W,et al.Abnormalities of maternal thyroid function during pregnancy affect neuropsychologi- cal development of their children at 25-30 months[J].Clin Endocrinol(Oxf),2010,72(6):825-829.
  • 6Negro R,Schwartz A,Gismondi R,et al.Universal screening versus case finding for detection and treatment of thyroid hormonal dysfunction during pregnancy[J],J Clin Endo- crinol Metab,2010,95(4): 1699-1707.
  • 7Horacek J,Spitalnikova S,Dlabalova B,et al.Universal screening detects two-times more thyroid disorders in early pregnancy than targeted high-risk case finding[J]. Eur J Endocrinol,2010,163(4):645-650.
  • 8Poppe K,Glinoer D,Tournaye H,et al.Assisted repro- duction and thyroid autoimmunity : an unfortunate combi- nation[J].J Clin Endocrinol Metab,2003,88(9): 4149-4152.
  • 9Vaidya B,Bilous M,Hutchinson RS,et al.Screening for thyroid disease in pregnancy: an audit[J].Clin Med,2005,(6):599-600.
  • 10于颖,张巍.胎儿甲状腺功能发育及其对胎儿脑发育的影响[J].中国妇幼健康研究,2010,21(3):378-380. 被引量:5

共引文献71

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部