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左旋甲状腺素治疗妊娠合并甲状腺功能减退对患者甲状腺功能及妊娠的影响

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摘要 目的观察左旋甲状腺素治疗妊娠合并甲状腺功能减退对患者甲状腺功能及妊娠的影响。方法将2016年3月~2018年1月我院收治的妊娠合并甲状腺功能减退患者110例按随机双盲法分为两组,各55例。对照组给予常规治疗,研究组给予左旋甲状腺素治疗。比较两组患者临床疗效、甲状腺功能及妊娠结局。结果治疗后,研究组总有效率(92.73%)高于对照组(72.73%),差异有统计学意义(P<0.05);两组患者治疗至分娩时,游离三碘甲腺原氨酸(FT3)、游离甲状腺素(FT4)升高,促甲状腺素(TSH)降低,研究组上述各指标改善较对照组明显,差异有统计学意义(P<0.05);研究组患者剖宫产、胎盘早剥、早产、新生儿畸形、低体重儿率均低于对照组,差异有统计学意义(P<0.05)。结论左旋甲状腺素治疗妊娠合并甲状腺功能减退疗效确切,可有效调节患者甲状腺功能水平,改善母婴妊娠结局,值得临床推广。
作者 张素盈
出处 《首都食品与医药》 2019年第23期90-91,共2页 Capital Food Medicine
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