中西医结合治疗复治肺结核的效果观察

Observation on the effect of integrative Chinese and Western medicine in the treatment of retreated tuberculosis

目的探讨抗痨胶囊联合西医抗结核药物治疗复治肺结核的效果。方法选取复治肺结核患者86例,分为观察组(利福平、异烟肼、乙胺丁醇、吡嗪酰胺、盐酸左氧氟沙星+抗痨胶囊),对照组(利福平、异烟肼、乙胺丁醇、吡嗪酰胺、盐酸左氧氟沙星),通过胸部CT病灶吸收情况、临床症状改善情况、痰涂片阴转情况进行对比分析。结果观察组治疗3个月末时痰涂片阴转率为91.11%,治疗组为70.73%(P<0.05);观察组治疗3个月末时胸部CT病灶吸收有效率为82.2%,对照组吸收有效率为58.5%,差异有统计学意义(P<0.05);观察组治疗后症状改善率为90.80%,对照组为70.97%,观察组治疗后临床症状改善率高于对照组,差异有统计学意义(P<0.05)。结论抗痨胶囊联合西医抗结核药物治疗复治肺结核可以相互辅助,提高治疗效果。

Objective To discuss the efficacy of anti-tuberculosis capsule combined with anti-tuberculosis western medicines for the treatment of retreated tuberculosis.Methods 86 patients with retreated tuberculosis were selected and divided into the observation group(rifampin,isoniazide,ethambutol,pyrazinamide,levofloxacin + anti-tuberculosis capsule) and the control group(rifampin,isoniazide,ethambutol,pyrazinamide,levofloxacin). The lesion absorption based on chest CT,clinical symptom improvement,negative conversion of sputum smear and occurrence of adverse drug reaction were compared and analyzed.Results The negative conversion rate of sputum smear was 91.11% in the observation group and 70.73% in the treatment group after treatment for three months(P<0.05).The effective absorption rate of chest CT lesions was 82. 2% in the observation group and 58. 5% in the control group( P < 0. 05). The improvement rate of symptoms was 90. 80% in the observation group and 70. 9% in the control group after treatment( P < 0. 05). The improvement rate of clinical symptoms in the observation group was higher than that in the control group( P < 0. 05). Conclusion Anti tuberculosis capsule combined with western medicines for retreated tuberculosis can complement each other and improve the therapeutic effect.