手术治疗脊柱嗜酸性肉芽肿临床病例特征分析

Clinical Characteristics of Spinal Eosinophilic Granuloma After Surgical Treatment

目的通过对儿童颈椎嗜酸性肉芽肿病例的回顾,进一步探讨其流行病学特征、影像学特征、组织病理学、鉴别诊断及治疗方法。方法1例8岁患儿因颈部疼痛伴右上肢疼痛入院,经保守治疗无效,接受颈椎肿物切除手术治疗。结果术后组织病理学结果证实肿物为嗜酸性肉芽肿。随访20个月未见复发,患儿神经、运动功能完好,已回归正常社会生活。结论脊柱嗜酸性肉芽肿是一种自限性疾病,早期阶段可积极采取保守治疗,保守无效且出现脊柱后凸畸形、神经功能损伤等病症需积极接受手术治疗,必要时结合放疗或化疗,可取得良好的预后效果。

Objective By reviewing the case of cervical eosinophilic granuloma in children,the epidemiological characteristics,imaging features,histopathology,differential diagnosis and treatment of cervical eosinophilic granuloma were further investigated.Methods An 8-year-old child was admitted for cervical pain with pain in the right upper extremity.After conservative treatment failure,he underwent cervical vertebral resection.Results The Postoperative histopathological results confirmed that the mass was eosinophilic granuloma.No recurrence was found in the follow-up of 20 months.The neurological and motor functions of the child were intact,and he had returned to normal social life.Conclusion Spinal eosinophilic granuloma is a self-limited disease that can be treated conservatively in the early stages.If the failure of conservative treatment leads to kyphosis and neurological impairment,surgical treatment is recommended as soon as possible.When necessary,surgical treatment combined with radiotherapy or chemotherapy can achieve better therapeutic effect.