两种不同微创方式治疗早期肺癌的临床疗效和对心肺并发症及预后的影响

Clinical Efficacy of Two Different Minimally Invasive Methods in the Treatment of Early Stage Lung Cancer and Its Influence on Cardiopulmonary Complications and Prognosis

目的探讨2种不同微创方式治疗早期肺癌的临床疗效和对心肺并发症及预后的影响。方法选取100例早期肺癌患者,根据手术方式的不同分为研究组与对照组。研究组采用单孔胸腔镜肺癌根治术治疗,对照组采用三孔胸腔镜肺癌根治术治疗,比较2组患者的临床疗效等差异。结果研究组治疗的总有效率(96.0%)与对照组(92.0%)比较,无统计学差异(P>0.05);研究组患者术后疼痛评分及切口长度均低于对照组患者(P<0.05),且研究组手术时间及术中出血量均高于对照组(P<0.05),而2组患者的术后带管时间、淋巴结清扫数目比较无统计学差异(P>0.05)。研究组患者术后心肺并发症总发生率(16.0%)与对照组(22.0%)比较,无统计学差异(P>0.05)。术后1年,2组患者FACT-L评分比较,研究组功能状态及总分均优于对照组(P<0.05)。结论单孔与三孔法胸腔镜早期肺癌根治术在临床疗效及对心肺功能影响相近的情况下,单孔法更具微创性,对减轻患者术后疼痛,加快患者康复及提高患者预后具有深远的临床价值,值得推广。

Objective To investigate the clinical efficacy of 2 different minimally invasive methods in the treatment of early stage lung cancer and its influence on cardiopulmonary complications and prognosis.Methods 100 patients with early stage lung cancer were enrolled and divided into the study group and the control group according to different surgical methods.The study group was treated with single-hole thoracoscopic radical mastectomy and the control group was treated with three-hole thoracoscopic radical mastectomy.The clinical efficacy of the 2 groups was compared.Results The total effective rate of treatment in the study group(96.0%)was not significantly different from that of the control group(92.0%)(P>0.05).The postoperativepain score and length of incision in the study group were lower than those of the control group(P<0.05).The operation time and intraoperative blood loss of the study group were higher than those of the control group(P<0.05),but there was no significant difference in the postoperative tube time and lymph node dissection between the 2 groups(P>0.05).The total incidence of postoperative cardiopulmonary complications(16.0%)in the study group was not significantly different from that of the control group(22.0%)(P>0.05).1 year after operation,the FACT-L scores of the 2 groups were better than those of the control group(P<0.05).Conclusion Single-hole and three-hole thoracoscopic early radical lung cancer surgery in the clinical efficacy and similar effects on cardiopulmonary function,single-hole method is more minimally invasive,to reduce postoperative pain,accelerate patient recovery and improve patient prognosis has far-reaching.The clinical value is worth promoting.