复方丹参滴丸联合阿司匹林肠溶片治疗冠心病的疗效观察

Curative Effect of Compound Danshen Dripping Pills Combined with Aspirin Enteric-Coated Tablet on Coronary Heart Disease

目的:探讨复方丹参滴丸联合阿司匹林肠溶片治疗冠心病(CHD)临床疗效。方法:选取2017年12月至2018年12月佛山市高明区慢性病防治站收治的CHD患者60例,随机均分对照组与观察组,各30例。对照组患者采取阿司匹林肠溶片治疗,观察组患者在对照组基础上口服复方丹参滴丸,观察两组患者的治疗效果、血液流变学和炎症因子水平。结果:观察组患者治疗后临床疗效有效率高于对照组,差异具有统计学意义(P <0.05);观察组治疗后高切全血黏度、低切全血黏度、血浆黏度、肿瘤坏死因子(TNF–α)、白细胞介素–6(IL–6)均低于对照组,IL-10含量高于对照组,差异均具有统计学意义(P <0.05)。结论:两种药物联合治疗CHD临床效果良好。

Objective To explore the curative effect of compound Danshen Dripping pills and aspirin enteric-coated tablet on coronary heart disease(CHD). Methods From December 2017 to December 2018, in Foshan Gaoming district chronic disease prevention and treatment station, 60 CHD patients admitted to the station were randomly divided into control group and observation group, 30 cases in each group. The control group was given aspirin enteric-coated tablets. On this basis, the observation group was given compound Danshen Dripping pills for oral administration, the clinical curative effect in both groups were observed. Results After treatment, the response rate of clinical curative effect in observation group was higher than that in the control group(P < 0.05). After treatment, high-shear and low-shear whole blood viscosity, plasma viscosity, TNF-α and IL-6 of the observation group were lower than those of the control group, while IL-10 content was higher than that of the control group. Differences are statistically significant(P < 0.05). Conclusion The clinical curative effect of their combination treatment is significant on CHD.