补阳还五汤联合微创钻孔引流术治疗慢性硬膜下血肿的临床效果

Clinical effect of Buyang Huanwu decoction combined with minimally invasive drilling and drainage in the treatment of chronic subdural hematoma

目的探讨补阳还五汤联合微创钻孔引流术治疗慢性硬膜下血肿(CSDH)的临床效果。方法选取2013年6月至2018年6月我院收治的88例CSDH患者为研究对象,根据治疗方式的不同将其分为对照组(44例,微创钻孔引流术治疗)与观察组(44例,微创钻孔引流术治疗+补阳还五汤)。对比两组患者的治疗效果。结果观察组的治疗总有效率高于对照组(P<0.05)。观察组的血肿复发率略低于对照组(P>0.05)。术后10、30、90 d,观察组的血肿残余量百分比均明显低于对照组(P<0.05)。术后30、90 d,两组的IL-6及TNF-α水平均较术前明显降低,且观察组低于对照组(P<0.05)。术后30 d,两组的生活质量各项评分均明显升高,且观察组高于对照组(P<0.05)。结论补阳还五汤联合微创钻孔引流术治疗CSDH效果显著,可以减少血肿残余量,减轻炎症反应,提高患者的生活质量,值得临床推广。

Objective To explore the clinical effect of Buyang Huanwu decoction combined with minimally invasive drilling and drainage in the treatment of chronic subdural hematoma(CSDH). Methods Eighty-eight CSDH patients admitted in our hospital from June 2013 to June 2018 were selected as the study objects. According to the different treatment methods, the patients were divided into control group(44 cases, minimally invasive drilling and drainage treatment) and observation group(44 cases, minimally invasive drilling and drainage treatment+Buyang Huanwu decoction).The therapeutic effects of the two groups were compared. Results The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05). The recurrence rate of hematoma in the observation group was slightly lower than that in the control group(P >0.05). At 10, 30, 90 days after operation, the percentage of residual hematoma in the observation group was significantly lower than that in the control group(P<0.05). At 30 and 90 days after operation, the levels of IL-6 and TNF-α in the two groups were significantly lower than those before operation, and those in the observation group were lower than the control group(P<0.05). At 30 days after operation, the scores of quality of life in the two groups increased significantly, and those of the observation group were higher than the control group(P<0.05).Conclusion Buyang Huanwu decoction combined with minimally invasive drilling and drainage is effective in the treatment of CSDH, it can decrease the residual amount of hematoma, reduce the inflammatory reaction, and improve the quality of life of patients, which is worthy of clinical promotion.