三子养亲汤加减对肺气虚型尘肺病患者中医证候的影响

Effect of modified Sanzi Yangqin decoction on TCM syndrome in patients with pneumoconiosis of lung qi deficiency type

目的研究三子养亲汤加减对肺气虚型尘肺病患者中医证候的影响。方法选择2018年1月1日至2018年12月31日我院收治的,且由两名以上中医主治医师辨证为肺气虚型尘肺病患者60例,将其随机分为对照组和试验组,每组30例。对照组患者给予常规治疗,试验组患者在常规治疗基础上给予三子养亲汤加减治疗。两组疗程均为1个月。比较两组患者治疗前、后中医证候积分。结果治疗前,两组患者中医证候主症积分比较,差异无统计学意义(P>0.05);治疗后,试验组喘促气短积分显著低于对照组,差异具有统计学意义(P<0.05);两组咳声低弱、易患感冒积分比较,差异无统计学意义(P>0.05)。治疗前,两组中医证候总积分比较,差异无统计学意义(P>0.05);治疗后,两组中医证候总积分显著降低,且试验组低于对照组,差异具有统计学意义(P<0.05)。结论三子养亲汤加减可使肺气虚型尘肺病患者临床症状减轻,尤其是主证"喘促气短",进而提高患者生活质量。

Objective To study the effect of modified Sanzi Yangqin decoction on TCM syndromes in patients with pneumoconiosis of lung qi deficiency type. Methods From January 1, 2018 to December 31, 2018, 60 patients with pneumoconiosis of lung qi deficiency type were selected and diagnosed by more than two doctors in charge of traditional Chinese medicine and randomly divided into control group and experimental group, with 30 cases in each group. Patients in the control group were treated with conventional treatment, and the experimental group were treated with modified Sanzi Yangqin decoction on the basis of conventional treatment. The course of treatment in both groups were one month. The scores of TCM syndromes before and after treatment were compared between the two groups. Results Before treatment, there was no significant difference in main symptom scores of TCM syndromes between the two groups(P>0.05);after treatment,the score of dyspnea and shortness of breath in the experimental group was significantly lower than that in the control group, and the difference was statistically significant(P<0.05);there were no significant differences between the two groups in the scores of low cough and catch cold easily(P>0.05). Before treatment, there was no significant difference in the total score of TCM syndrome between the two groups(P >0.05);after treatment, the total score of TCM syndromes in the two groups decreased significantly, and that in the experimental group was lower than the control group, the difference was statistically significant(P <0.05). Conclusion Modified Sanzi Yangqin decoction can reduce the clinical symptoms of pneumoconiosis patients with lung qi deficiency type, especially the main syndrome of "dyspnea and shortness of breath",and so as to improve the patients’ quality of life.