中等强度有氧运动对中老年男性原发性高血压患者24 h动态血压、生活质量和糖脂代谢的影响分析

Effects of moderate intensity aerobic exercise on 24 h ambulatory blood pressure, quality of life and glucose and lipid metabolism in middle-aged and older males with primary hypertension

目的探讨中等强度有氧运动对中老年男性原发性高血压患者24 h动态血压、生活质量和糖脂代谢的影响。方法选取2018年6月至2019年6月本院收治的中老年男性原发性高血压患者122例为研究对象。依据随机数表法将入选患者分为观察组和对照组,每组各61例。两组患者均采取常规降压药物治疗,观察组患者在此基础上进行中等强度有氧运动。两组患者疗程均为12周。比较两组患者干预前后24 h舒张压和收缩压变化、生活质量改善情况、糖脂代谢指标变化。结果两组患者干预前24 h舒张压和收缩压、SF-36量表4个维度评分比较差异均无统计学意义(均P>0.05)。两组患者干预后24 h舒张压和收缩压均显著低于本组干预前(均P<0.05),SF-36量表4个维度评分均显著高于本组干预前(均P<0.05);观察组患者干预后24 h舒张压和收缩压均显著低于对照组(均P<0.05),SF-36量表各维度评分均显著高于对照组(均P<0.05)。两组患者干预前后空腹血糖、糖化血红蛋白、餐后2 h血糖、高密度脂蛋白胆固醇、总胆固醇、低密度脂蛋白胆固醇和甘油三酯水平组间和组内比较差异均无统计学意义(均P>0.05)。结论中等强度有氧运动可降低中老年男性原发性高血压患者血压,改善患者生活质量,但对糖脂代谢无明显影响。

Objective To investigate the effect of moderate intensity aerobic exercise on 24 h ambulatory blood pressure,quality of life and glucose and lipid metabolism in middle-aged and older males with primary hypertension.Method A total of 122 middleaged and older males with primary hypertension admitted from June 2018 to June 2019 in our hospital were randomly divided into observation group(61 cases)and control group(61 cases).Both groups were treated with conventional antihypertensive drugs.Patients in observation group took moderate intensity aerobic exercise.The course of treatment in both groups was 12 weeks.The changes of 24 h diastolic and systolic blood pressure,quality of life improvement,glucose metabolism and lipid metabolism were compared between the two groups before and after intervention.Result There were no significant differences in 24 h diastolic and systolic blood pressure,4 dimensions of SF-36 scores between the two groups before intervention(all P>0.05).The 24h diastolic and systolic blood pressure of the two groups after intervention were significantly lower than those before intervention(all P<0.05),and the 4 dimensions of SF-36 scores were significantly higher than those before intervention(all P<0.05);the 24 h diastolic and systolic blood pressure of observation group were significantly lower than those of control group(all P<0.05),and the 4 dimensions of SF-36 scores were significantly higher than those of control group(all P<0.05).There were no significant differences of fasting blood glucose,2-h plasma glucose concentration,glycated hemoglobin A1c,high density lipoprotein cholesterol,total cholesterol,low density lipoprotein cholesterol,triglyceride between the two groups before and after intervention(all P>0.05).Conclusion Moderate intensity aerobic exercise can reduce the blood pressure and improve the quality of life of middle-aged and older males with primary hypertension,but it has no significant effect on glucose and lipid metabolism.