欧洲凤尾蕨化学成分的研究

Chemical constituents from Pteris cretica

目的研究欧洲凤尾蕨Pteris cretica L.的化学成分。方法欧洲凤尾蕨95%乙醇提取物采用硅胶、Sephadex LH⁃20、C18半制备柱等进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构。结果从中分离得到13个化合物,分别鉴定为洋芹素⁃7⁃O⁃鼠李糖苷(1)、4′,5,7⁃三羟基黄酮(2)、芹菜素⁃7⁃O⁃β⁃D⁃葡萄糖苷(3)、木犀草素⁃7⁃O⁃β⁃D⁃葡萄糖苷(4)、5,7⁃dihydroxychromone⁃7⁃O⁃neohesperidoside(5)、(-)⁃异落叶松树脂醇3⁃α⁃O⁃β⁃D⁃葡萄糖苷(6)、7S,8R⁃二氢去氢双松柏醇(7)、松脂醇⁃4⁃O⁃β⁃D⁃葡萄糖苷(8)、7⁃β⁃D⁃glucosyloxy⁃5⁃hydroxy⁃chromone(9)、邻苯二甲酸二正丁基酯(10)、3⁃甲氧基⁃4⁃O⁃β⁃D⁃吡喃葡萄糖基苯甲酸甲酯(11)、phenylβ⁃D⁃glucopyranoside(12)、dearabinosyl pneumonanthoside(13)。结论所有化合物均为首次从该植物中分离得到,除化合物2、4、11外,均为首次从凤尾蕨属中分离得到。

AIM To study the chemical constituents from Pteris cretica L..METHODS The 95%ethanol extract from P.cretica was isolated and purified by silica,Sephadex LH⁃20 and C18 semi⁃preparative column,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Thirteen compounds were isolated and identified as apigenin⁃7⁃O⁃rhamnoside(1),4′,5,7⁃trihydroxyflavone(2),apigenin⁃7⁃O⁃β⁃D⁃glucoside(3),luteolin⁃7⁃O⁃β⁃D⁃glucoside(4),5,7⁃dihydroxychromone⁃7⁃O⁃neohes⁃peridoside(5),(-)⁃isolariciresinol 3⁃α⁃O⁃β⁃D⁃glucopyranoside(6),7S,8R⁃dihydrodehydroconiferyl alcohol(7),pinoresinol⁃4⁃O⁃β⁃D⁃glucoside(8),7⁃β⁃D⁃glucosyloxy⁃5⁃hydroxy⁃chromone(9),1,2⁃benzenedicarboxylic acid⁃dibuty ester(10),3⁃methoxyl⁃4⁃O⁃β⁃D⁃glucopyranosyloxybenzoic acid methyl ester(11),phenylβ⁃D⁃gluco⁃pyranoside(12),dearabinosyl pneumonanthoside(13).CONCLUSION All the compounds are isolated from this plant for the first time,and the rest except compounds 2,4,11 are first isolated from genus Pteris.