儿童腺样体扁桃体切除术后体质量变化的初步临床研究

A preliminary clinical study of body mass changes after adenoidectomy in children

目的研究儿童腺样体扁桃体切除术与术后体质量变化的相关性.方法选取本院120例进行腺样体扁桃体切除术符合纳入标准的儿童为研究对象,其中28例反复急性扁桃体感染,睡眠呼吸暂停低通气指数(AHI)<1的儿童纳入扁桃体反复感染组;92例术前AHI≥1的儿童纳入阻塞性睡眠呼吸暂停低通气综合征(OSAHS)组.收集患儿年龄、性别、AHI、术前及术后3、6个月体质量指数z评分(BMIzsc),根据研究表明的腺样体扁桃体切除术的平均年龄为5.6岁,将患者分为年龄≤6岁组和>6岁组,比较2组术前、术后BMIzsc变化.结果扁桃体反复感染组与OSAHS组在年龄、性别、术前身高、术前体质量、术前及术后BMIzsc等方面差异均无统计学意义(P>0.05).2组术前BMIzsc评分与术后比较差异有统计学意义(P<0.05).多重线性回归分析显示,术后BMIzsc与性别、AHI无相关性,与年龄呈负相关性,差异有统计学意义(P<0.05).结论腺样体扁桃体切除术对年龄≤6岁儿童体质量增加有较大影响.

Objective To study the correlation between adenotonsillectomy and postoperative body mass index change.Methods A total of 120 children with adenotonsillectomy meeting the inclusion criteria were selected as the study objects.Among them,28 children with recurrent acute tonsillar infection and sleep apnea hypopnea index(AHI)<1 were included in the recurrent tonsillar infection group,while 92 children with preoperative AHI≥1 were included in the obstructive sleep apnea hypopnea syndrome(OSAHS)group.Age,gender,AHI,body mass index z-scores(BMIzsc)at 3-to 6-month before and after operation were compared.According to a previous studies revealing that the mean age undergoing adenotonsillectomy was 5.6 years,these patients were divided into≤6 years and>6 years.The changes of BMIzsc before and after operation were compared.Results There were no significant differences in age,sex,height before operation,body mass before operation,BMIzsc before and after operation between the two groups(P>0.05),but a significant difference was found in postoperative BMIzsc scores compared with operation before in two groups(P<0.05).Multiple linear regression analysis demonstrated that BMIzsc had no correlation with sex,and AHI,but was negatively correlated with age(P<0.05).Conclusion Adenotonsillectomy has a significant effect on the body mass of children under 6 years old.