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非糜烂性反流病患者食管动力及24h pH-阻抗特点分析 被引量:6

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摘要 目的 研究非糜烂性反流病(NERD)患者食管动力及24hpH-阻抗特征。方法 选取2017年5月至2018年12月在该院消化内科就诊的NERD患者20例(NERD组)及同期健康体检者13例(对照组),对其进行一般状况、食管动力及24hpH-阻抗监测等方面的比较分析。结果 NERD组中远端收缩积分(DCI)及食管下括约肌(LES)静息压(LESP)明显低于对照组(P<0.05);蠕动中断较对照组明显延迟(P<0.05);两组间远端潜伏时间及LES腹内长度(LESL)无明显差异(P>0.05)。NERD组患者DeMeester评分、酸反流、液体反流及混合反流次数明显高于对照组(P<0.05);两组弱酸反流、无酸反流、气体反流次数无明显差异(P>0.05)。酸反流与LESP、LESL呈负相关(r=-0.397,P=0.022;r=-0.433,P=0.012)。结论 NERD患者食管体部蠕动功能减弱,LESP明显降低,酸反流及液体反流次数增加,酸反流主要与LESP呈负相关,但与食管体部蠕动功能无明显相关性。
出处 《重庆医学》 CAS 2019年第23期4111-4113,共3页 Chongqing medicine
基金 胃肠早癌体外诊断产品研发创新团队项目(2017C110019)
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