结直肠癌患者应用卡培他滨辅助化疗的不良反应及人文关怀护理效果

Adverse Reactions of Capecitabine Adjuvant Chemotherapy in Patients with Colorectal Cancer and the Effect of Humanistic Care

目的:探讨结直肠癌患者应用卡培他滨辅助化疗的不良反应及人文关怀护理。方法:选定2017年5月至2019年2月到本院接受治疗的146例结直肠癌患者,随机分为对照组73例(卡培他滨联合基础护理)与观察组73例(卡培他滨联合人文护理),比较两组周围环境、生理状况、社会关系、心理状态、有效率与不良反应发生率指标指标。结果:观察组有效率指标(93.15%)高于对照组(73.97%)且差异具有统计学意义(P<0.05);观察组周围环境、生理状况、社会关系、心理状态等指标评分均高于对照组且差异具有统计学意义(P<0.05);观察组不良反应发生率(13.70%)低于对照组(43.84%)且差异具有统计学意义(P<0.05)。结论:卡培他滨联合人文护理方法可有效改善结直肠癌患者预后,减少其不良反应,值得推广使用。

Objective: To investigate the adverse reactions of capecitabine adjuvant chemotherapy and humanistic care in patients with colorectal cancer. Methods: 146 patients with colorectal cancer who were treated in our hospital from May 2017 to February 2019 were randomly divided into control group(73 cases of capecitabine combined with basic nursing)and observation group(73 cases of capecitabine combined with humanistic nursing). The surrounding environment, physiological status, social relations, psychological status, efficiency and incidence of adverse reactions were compared between the two groups. Results: The effective rate index(93.15%)of the observation group was higher than that of the control group(73.97%)and the difference was statistically significant(P<0.05);the scores of the surrounding environment, physiological status, social relations and psychological status of the observation group were higher than those of the control group and the difference was statistically significant(P<0.05);The incidence of adverse reactions in the observation group(13.70%) was lower than that in the control group(43.84%), the difference was statistically significant(P<0.05). Conclusion: Capecitabine combined with humanistic nursing can effectively improve the prognosis of patients with colorectal cancer and reduce its adverse reactions, which is worth promoting.