脉络膜新生血管的光学相干断层扫描血管成像和荧光素血管造影的特征分析

Characteristics of choroidal neovascularization in optical coherence tomography angiography versus fluorescein angiography

目的探讨脉络膜新生血管(CNV)的光学相干断层扫描血管成像(OCTA)和荧光素血管造影(FFA)的特征。方法回顾诊断为CNV的116例患者的临床资料,排除瘢痕期的病灶,共116眼,分析患者同期进行的OCTA和FFA检查的特征。结果CNV在OCTA中表现为肾小球形的最多(占48.3%),其中病灶周围有黑晕的占64.3%;其次为美杜莎形(占36.2%),病灶周围有黑晕的占71.4%;最少的为枯树枝状CNV(占15.5%),其中病灶周围有黑晕的比例为22.2%。在FFA检查中,无源性渗漏和经典型渗漏占比分别为58.6%和41.4%,无源性渗漏中合并出血、渗出及色素紊乱者分别占50.0%、38.2%和35.3%。OCTA中表现为肾小球形合并周围黑晕的病灶占经典型渗漏的37.5%,表现为美杜莎形合并周围黑晕的病灶占经典型渗漏的25.0%,表现为枯树枝状且周围无黑晕的病灶占经典型渗漏的16.7%。结论与FFA相比,OCTA检查技术具有非接触性、扫描速度快、分辨率高的优点。

Objective To investigate the characteristics of choroidal neovascularization(CNV)in optical coherence tomography angiography(OCTA)versus fluorescein angiography(FFA).Methods The data of 116 patients with CNV diagnosed in our hospital were retrospectively reviewed,and 116 eyes were included in study after exclusion of those in scar stages.The characteristics of OCTA and FFA conducted in theses eyes in the same period were analyzed.Results OCTA results showed that the glomerulus-shaped CNV accounted for the most proportion(48.3%),followed by Medusa-shaped(36.2%)and withered tree-shaped(15.5%),and the darkness around lesions accounted for 64.3%,71.4%and 22.2%,respectively.FFA showed that the proportions of passive leakage and typical leakage were 58.6%and 41.4%,respectively,and the proportions of passive leakage combined with hemorrhage,exudation and pigmentation disorder were 50.0%,38.2%and 35.3%,respectively.OCTA showed that the ratios of glomerulus-shaped or Medusa-shaped lesions combined with darkness around lesions to typical leakage were 37.5%,25.0%,respectively,and the withered tree-shaped lesions combined with darkness to typical leakage ratio was 16.7%.Conclusion Compared with FFA,OCTA has the advantages of non-contact,fast scanning and high resolution.