围术期电针刺激对七氟醚全麻患者术后嗅觉记忆的影响

Effect of Perioperative Electroacupuncture on Postoperative Olfactory Memory in Patients with General Anesthesia of Sevoflurane

目的:观察围术期电针刺激迎香穴和印堂穴对七氟醚全麻患者术后嗅觉记忆的影响。方法:择期在全身麻醉下行妇科、泌尿科等手术的成年患者40例,随机均分为电针干预组(E组)和七氟醚组(S组),电针干预组选取迎香穴(双侧)和印堂穴于麻醉诱导前10min进行电针刺激然后行全身麻醉、电针刺激至手术结束,七氟醚组不予电针处理、麻醉方法与电针干预组相同;记录2组患者麻醉诱导前(T0)、手术开始后30min(T 1)和手术结束时(T2)的平均动脉压(MAP)、心率(HR)、脉搏氧饱和度(SpO2)及术中七氟醚用量;于麻醉诱导前(T0)和手术后当Aldrete评分达10分时(T3),采用康涅狄格化学感觉临床研究中心(CCCRC)嗅觉检查法进行嗅觉识别检测,比较2组患者嗅觉识别得分。结果:与干预组比较,七氟醚组T 0时点嗅觉识别分值比较差异无统计学意义(P>0.05),七氟醚组T 3时点嗅觉识别分值降低,差异有统计学意义(P<0.05);与七氟醚组比较,七氟醚组T 3时点嗅觉识别分值降低,差异有统计学意义(P<0.05),2组患者性别构成、年龄、BMI等一般情况和术中情况差异无统计学意义(P>0.05)。结论:电针刺激迎香穴和印堂穴可提高七氟醚全麻患者术后嗅觉记忆得分,改善全麻手术患者术后嗅觉记忆障碍。

Objective:To observe the effect of perioperative electroacupuncture Yingxiang and Yintang acupoints on postoperative olfactory memory in patients with General Anesthesia of Sevoflurane.Methods:Forty adult patients with gynecological and urological procedures with general anesthesia,aged 18~60 years,were randomly divided into the electroacupuncture intervention group(group E)and the sevoflurane group(group S),20 cases in each group.In group E:Electroacupuncture was administered to patients at Yingxiang(two sides)(LI 20)and Yintang(GV 29)acupoints from 10 minutes before anesthesia to the end of operation;then general anesthesia was performed.In group S,patients did not not receive electroacupuncture stimulation,the method of anesthesia was the same as that of group E.The mean arterial pressure(MAP),heart rate(HR)and oxygen saturation(SpO 2)were recorded before induction of anesthesia(T 0),30 min after surgery(T 1)and at the end of surgery(T 2).The dosage of sevoflurane during operation was calculated.Olfactory memory was tested using the olfactory test of Connecticut Chemosensory Clinical Research Center(CCCRC);the scores were recorded before induction of anesthesia(T 0)as the Aldrete Recovery Score reached 10(T 3)in the postoperative period.Results:Compared with group E,there was no significant difference of the olfactory recognition scores of group S in T 0;the olfactory recognition scores of group S in T 3 decreased(P<0.05).Compared with group S,the olfactory recognition scores of group S in T 3 decreased(P<0.05).There was no statistically difference of baseline characteristics between both groups(such as gender composition,age and BMI)during the operation.Conclusion:Electroacupuncture Yingxiang and Yintang acupoints can improve the olfactory memory scores of patients with general anesthesia of sevoflurane and improve the occurrence of the olfactory memory disorder after general anesthesia.