一期清创内固定治疗原发性化脓性脊柱感染

One-stage debridement and instrumentation in treament of primary suppurative spine infection

目的探讨抗生素+清创+内固定治疗原发性化脓性脊柱感染的效果。方法从病死率、一期治愈率、感染复发率3方面比较单用抗生素、抗生素+清创、抗生素+清创+内固定3种方式治疗20例原发性化脓性脊柱感染患者的临床疗效。结果患者均获得随访,时间9个月~6年。病死率、感染复发率3种治疗方式比较差异无统计学意义(P>0.05);抗生素+清创+内固定治疗方式一期治愈率更高(P<0.05)。结论在原发性化脓性脊柱感染患者中应用抗生素+清创+内固定治疗是安全的,一期治愈率更高。

Objective To investigate the clinical effects of antibiotics plus debridement and instrumentation in treament of primary suppurative spine infection.Methods The effect of 20 cases with primary suppurative spine infection were compared in three aspects of mortality,the first stage cure rate and reinfection rate,who were treated with antibiotics alone,antibiotics with debridement,and antibiotics plus debridement and instrumentation.Results All cases were followed up for 9~72 months.There were no statistical differences in terms of mortality or reinfection rates for patients treated with three treatment methods(P>0.05);however,the first stage cure rate was higher for patients treated with antibiotics plus debridement and instrumentation(P<0.05).Conclusions The antibiotics plus debridement and instrumentation in primary suppurative spine infection is safe,and the first stage cure rate is higher.