摘要
建立手持式拉曼快速鉴别部分头孢菌素类原料方法。方法:采用对照品建立拉曼光谱图库,用命中率指数(hit quality index,HQI)进行评价。结果:阳性样品HQI均大于0.98,阴性样品的HQI均小于0.90,420批样品验证鉴定正确率100%。结论:手持式拉曼光谱仪方法简便、准确,可以用于头孢菌素类企业生产快速鉴别。
To establish a handheld Raman spectrometer method for rapid identification of some cephalosporins API.A Raman spectral library was constructed by reference substance,and the hit quality index(HQI)was used for evaluation.Results:The HQI of positive samples was greater than 0.98 and the negative samples was less than 0.90.Correct rate of identification of 420 batch samples was 100%.The method of handheld Raman spectrometer is simple and accurate,and can be used for rapid identification in cephalosporins production.
作者
冯丽雄
彭莺
万恒兴
Feng Lixiong;Peng Ying;Wang Hengxing(Shenzhen Institute of Technology,Shenzhen 518116,China)
出处
《山东化工》
CAS
2019年第23期117-119,124,共4页
Shandong Chemical Industry
基金
深圳技师学院科研项目(1811007)
关键词
命中率指数
鉴别
头孢菌素类
手持式拉曼光谱
hit quality index
identification
cephalosporins
handheld Raman spectrometer