清郁安神汤辅助治疗对稳定期COPD患者急性发作频次及睡眠质量的疗效观察

Effects of Qingyu Anshen Decoction Adjuvant Therapy on Acute Attack Frequency and Sleep Quality in Patients with Stable COPD

目的:观察清郁安神汤对稳定期慢性阻塞性肺疾病(Chronic Obstructive Pulmonary Disease,COPD)患者急性发作频次及睡眠质量的疗效。方法:选取2017年6月至2018年12月东南大学医学院附属南京市胸科医院呼吸科诊治的稳定期COPD患者60例作为研究对象,按照随机数字表法分为对照组和观察组,每组30例。对照组采用常规西药治疗,观察组在此基础上加以清郁安神汤辅助治疗。治疗3个月后,观察2组患者治疗期间急性发作频次,用匹兹堡睡眠指数量表(Pittsburgh Sleep Quality Index,PSQI)评估患者的睡眠情况。结果:经过治疗后,观察组患者的急性发作频次明显低于对照组(P<0.05);治疗前,2组患者的PSQI各项评分差异无统计学意义(P>0.05),治疗后,2组患者各项指标评分均下降,且观察组较对照组下降明显(P<0.05)结论:清郁安神汤辅助治疗稳定期COPD疗效理想,能够有效减少患者急性发作频次,改善患者睡眠质量,值得推广和使用。

Objective:To observe effects of Qingyu Anshen Decoction adjuvant therapy on acute attack frequency and sleep quality in patients with stable chronic obstructive pulmonary disease(COPD).Methods:Sixty patients with stable COPD who were admitted to Department of Respiration,Nanjing Chest Hospital of Medical School Of Southeast University from June 2017 to December2018 were enrolled.They were divided into control group and observation group by random number table method,and 30 cases in each group.The control group was treated with routine western medicine.On this basis,observation group was additionally given Qingyu Anshen Decoction for adjuvant therapy.After 3 months of treatment,acute attack frequency during treatment period in both groups was observed.Pittsburgh Sleep Quality Index(PSQI)was performed to assess sleep conditions of patients.Results:After treatment,acute attack frequency in observation group was significantly lower than that in control group(P<0.05).Before treatment,there was no significant difference in PSQI scores between the two groups(P>0.05).After treatment,scores of all indexes in both groups were decreased.And the decrease in observation group was more significant than that in control group(P<0.05).Conclusion:The effect of Qingyu Anshen Decoction is ideal in adjuvant treatment of patients with stable COPD,which can effectively reduce acute attack,and improve their sleep quality.