低剂量螺旋CT对高危人群的肺癌筛查结果分析

Screening of Lung Cancer in High-risk Group with Low-dose Spiral CT

[目的]了解低剂量螺旋CT对高危对象进行肺癌筛査的特点。[方法]对上海市闵行区36924名肺癌高危人群于2014-2016年间进行低剂量螺旋CT肺癌筛査,根据筛查结果,分别按性别、年龄段进行分组,比较肺癌检出率、病理分型及临床分期。[结果]低剂量螺旋CT筛査共检出肺癌患者273例,总检出率为0.74%,其中男性143例,女性130例;腺癌、鳞癌、小细胞癌及未分型分别为166例、4例、9例及94例,0~1期、2~3期及4期和未分期分别为118例、22例、13例及120例。肺癌总检出率、腺癌构成比、腺癌检出率女性均高于男性。男性肺癌检出率随年龄增长呈上升趋势,女性肺癌检出率随年龄增长呈上升趋势,到70-79岁年龄段出现小幅下降,后又呈上升趋势。[结论]采用低剂量螺旋CT对高危人群进行肺癌筛查有助于肺癌的早期发现并提高肺癌检出率,应在该人群中积极开展。

[Purpose]To analyze the results of screening of lung cancer in high risk population with low-dose spiral CT.[Methods]Lung cancer screening with low-dose spiral CT was carried out from 2014 to 2016 in Minhang district for 36924 high risk subjects.According to the results of screening,the lung cancer detection rate,pathological type and pathological stage in individuals of different gender and age were analyzed.[Results]Among all subjects 273 cases of lung cancer were detected and diagnosed pathologically with a detection rate of 0.74%.In detected lung cancer patients there were 143 males and 130 females;there were 166 cases of adenocarcinoma,4 cases of squamous carcinoma,9 cases of small cell carcinoma and 94 undefined cases;there were 118 of clinical stage 0〜1,22 cases of age 2-3,13 cases of stage 4 and 120 cases of undefined stages.The lung cancer detection rate,the proportion of adenocarcinoma were higher in females than those in males.The detection rates of lung cancer increased with the age for males.The detection rates of lung cancer increased with age for females before 70,and after 79 years.[Conclusion]Lung cancer screening with low-dose spiral CT can improve detection rate in high risk population.