期刊文献+

血流动力学与脑部血管周围间隙扩大关系的研究进展 被引量:3

Advance in Relationship between Cerebral Hemodynamics and Enlarged Perivascular Space
下载PDF
导出
摘要 脑部血管周围间隙扩大是脑小血管病的影像学标志物之一,其发生发展的机制尚不明确。现有研究表明血流动力学改变可能引起血管周围间隙扩大的发生发展。本文从血压、血管管壁僵硬程度、脑血流量等因素对血管周围间隙扩大的影响作一简要综述,为探索血管周围间隙扩大的发病机制及可能的治疗方法提供帮助。 The enlarged perivascular space is one of the neuroimaging markers of cerebral small vessel disease. The mechanism of perivascular space enlargement is still unclear. Many studies have shown that abnormal hemodynamics may be correlated with the enlarged perivascular space. This article reviewed the relationship between blood pressure, stiffness of vessel wall and cerebral blood flow with the enlarged perivascular space, to provide reference for studies of pathogenesis and possible treatment methods of enlarged perivascular space.
作者 马琳 王伊龙 MA Lin;WANG Yi-Long(Department of Neurology,Beijing Tian Tan Hospital,Capital Medical University/China National Clinical Research Center for Neurological Diseases,Beijing 100070,China)
出处 《中国卒中杂志》 2019年第11期1124-1128,共5页 Chinese Journal of Stroke
基金 国家自然科学基金委员会杰出青年科学基金项目(81825007) 北京高校卓越青年科学家计划项目(BJJWZYJH01201910025030) 科技部“十三五”国家重点研发计划“症状性颅内外大动脉狭窄复发进展预测模型与干预策略研究”(2017YFC1307900) 北京市科学技术委员会“动脉粥样硬化性颅内动脉狭窄的他汀药物治疗研究”(D171100003017001) 北京市优秀人才培养资助青年拔尖团队(2016000021223TD03)
关键词 血流动力学 血管周围间隙扩大 脑小血管病 Hemodynamics Enlarged perivascular space Cerebral small vessel disease
  • 相关文献

参考文献2

二级参考文献53

  • 1Aukland K, Reed RK. Interstitial-lymphatic mechanisms in the control of extracellular fluid volume[J]. Physiol Rev, 1993,73 : 1 - 78.
  • 2Esiri MM, Gay D. Immunological and neu- ropathological significance of the Virchow- Robin space[J]. J Neurol Sci,1990,100:3- 8.
  • 3Cserr HF, Harling Berg CJ, Knopf PM. Drainage of brain extracellular fluid into blood and deep cervical lymph and its immu- nological significance [J]. Brain Pathol, 1992,2:269-276.
  • 4Abbott NJ. Evidence for bulk flow of brain interstitial fluid, significance for physiology and pathology[J]. Neurochem Int, 2004,45 : 545-552.
  • 5Schley D, Carare-Nnadi R, Please CP, et al. Mechanisms to explain the reverse perivascu- lar transport of solutes out of the brain[J]. J Theor Biol, 2006,238 :962- 974.
  • 6Weller RO, Subash M, Preston SD, et al.Perivascular drainage of amyloid-beta pep- tides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's disease[J]. Brain Pathol, 2008,18 : 253- 266.
  • 7Ball KK, Cruz NF, Mrak RE;, et al. Traffic- king of glucose, lactate, and amyloid-beta from the inferior colliculus through perivas- cular routes[J]. J Cereb Blood Flow Metab, 2010,30.162-176.
  • 8Tian GF, Takano T, Lin JH, et al. Imaging of cortical astrocytes using 2-photon laser scanning microscopy in the intact mouse brain[J]. Adv Drug Deliv Rev, 2006, 58. 773-787.
  • 9Beanger M, Allaman I, Magistretti PJ. Brain energy metabolism, focus on astrocyte-neu- ron metabolic cooperation [J]. Cell Metab, 2011,14.724-738.
  • 10Kida S, Weller RO, Zhang ET, et al. Ana- tomical pathways for lymphatic drainage of the brain and their pathological significance [J]. Neuropathol Appl Neurobiol, 1995,21 : 181-184.

共引文献13

同被引文献43

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部