急性脑梗死静脉溶栓治疗后所致脑出血的研究进展

Research progress of cerebral hemorrhage after intravenous thrombolytic therapy for acute cerebal infartion

脑出血是急性脑梗死(ACI)静脉溶栓治疗后严重的并发症,可导致溶栓率降低.现就急性脑梗死静脉溶栓治疗后所致脑出血的定义与类型,以及基线美国国立卫生研究院卒中量表(NIHSS)评分、发病至溶栓时间、年龄、血压、心房颤动(AF)、血糖等因素进行综述,分析脑出血的危险因素,为实现患者个体化溶栓、提高溶栓疗效和降低出血性转化风险提供依据.

Cerebral hemorrhage is a serious complication after intravenous thrombolysis of acute cerebral infraction (ACI), which leads to low thrombolysis rate. In this paper, the factors such as definition and type of cerebal hemorrhage after intravenous thrombolysis of ACI, the baseline NIHSS score, the time from onset to hrombolysis, age, blood pressure, atrial fibrillation (AF), blood glucose, etc were reviewed in combination with recent litrrature. The risk factors of cerebral hemorrhage were analyzed to provide basis for achieving individualized hrombolysis, improving thrombolytic efficacy and reducing the risk of hemorrhagic transformation.