摘要
外伤性癫痫(posttraumatic epilepsy,P T E)系由创伤性脑损伤(traumatic brain injury,T B I)所致,可导致严重的伤、残,甚至死亡,目前仍缺乏P T E评定的客观方法。近年来,己有很多关于P T E遗传标记物的研究报道,其中一些具有很好的应用前景。因此,遗传生物标记物可能是P T E评定的客观标志。本文综述了P T E相关遗传标记物的研宄现状,为P T E的客观评定研宄提供借鉴。
Posttraumatic epilepsy (PTE) is caused by traumatic brain injury (TBI) ,which can lead to severe injury,disability, and even death. There is still a lack of objective methods to objectively evaluate PTE. In recent years, there havebeen many research reports on the genetic biomarkers of PTE, some of which have good application prospects. Therefore,genetic biomarkers may be an objective indicator on PTE assessment. This paper reviews the current research status of PTErelatedgenetic biomarkers and provides a reference for the objective evaluation of PTE.
作者
周凤娟
刘鸿霞
贾孝
代滨滨
王旭
杨天潼
(Zhou Fengjuan;Liu Hongxia;Jia Xiao;Dai Binbin;Wang Xu;Yang Tiantong(Key Laboratory of Evidence Science(China University of Political Science and Law,Ministry of Education,Beijing 100088,China;Collaborative Innovation Center of Judicial Civilization,Beijing 100088,China;China University of Political Science and Law Library,Beijing 100088,China)
出处
《中国法医学杂志》
CSCD
2019年第6期582-585,共4页
Chinese Journal of Forensic Medicine
基金
双一流-拔尖人才培养(2011-051040)
法医学山西省重点实验室资助
“中国政法大学青年教师学术创新团队支持计划资助(18CXTD09)
关键词
法医临床学
外伤性癫痫
遗传标记物
创伤性脑损伤
痫性发作
forensic clinical
posttraumatic epilepsy
genetic biomarker
traumatic brain injury
epileptic seizure
