2014年-2017年某医院麻醉药品与第一类精神药品应用情况分析

Analysis of the utilization of narcotic drugs and first class psychotropic drugs in a hospital from 2014 to 2017

目的:通过对某医院麻醉药品与第一类精神药品使用情况进行动态分析,进一步提高医院规范合理使用特殊药品的水平。方法:从医院计算机管理系统收集2014年-2017年麻醉药品与第一类精神药品的用药信息,计算各麻醉药品与第一类精神药品销售金额占全部麻醉药品与第一类精神药品销售金额的构成比、用药频度(DDDs)、限定日费用(DDC)、药物利用指数(DUI)等指标,并进行分析。结果:麻醉药品与第一类精神药品使用量在2014年-2017年呈现逐年上升趋势,枸橼酸芬太尼注射液销售金额居首位,且在2015年、2016年、2017年DDDs排序均为第一。盐酸哌替啶注射液用量呈下降趋势,其销售金额、DDDs、DUI在注射液中均为最小值,2017年开始不再使用。盐酸布桂嗪片在2015年后停止使用。盐酸氯胺酮注射液的DDC值始终最小。结论:麻醉药品和一类精神药品的使用情况基本合理,符合安全、有效、经济的用药原则,但仍然需要严格监管,使之更加安全、有效地应用于临床,实现规范化安全管理,更好地为广大患者服务。

Objective:To analyze the use of narcotics and the first class psychotropic drugs in the hospital in order to further improve the level of standard and rational use of drugs.Methods:The consumption data of narcotics and the first class psychotropic drugs in hospital from 2014 to 2017 retrieved from the hospital information system were analyzed with regard to the proportion of each narcotic drug or psychotropic drug in total narcotics or the first class psychotropic drugs in terms of the consumption sum,frequency of medication(DDDs),defined daily cost(DDC)and drug utilization index(DUI),etc.Results:The use of narcotic drugs and the first class psychotropic drugs in hospital increased year by year from 2014 to 2017.Among the narcotics and psychotropic drugs,fentanil injection ranked first in terms of consumption sum over 4 years,and it’s DDDs sorted first in 2015,2016 and 2017.The dosage of pethidine hydrochloride injection decreased,and the sales amount,DDDs and DUI were the minimum in the injection.It will not be used in 2017.Bucinnazine hydrochloride tablets were discontinued after 2015,and the smallest DDC was always ketamine hydrochloride.Conclusion:The use of narcotic drugs and first class psychotropic drugs conform to the specifications,in line with safe,effective and economical principles of medication,but they still need strict supervision to promote safe and effective use of them in the clinic,to achieve standardized safety management,better for the majority of patients.