中药穴位贴敷辅助治疗慢性阻塞性肺疾病急性加重期临床研究

Clinical Study on Point Application with Chinese Herbal Medicine for Acute Exacerbation of Chronic Obstructive Pulmonary Disease

目的:观察中药穴位贴敷辅助治疗慢性阻塞性肺疾病急性加重期(AECOPD)的临床疗效。方法:将90例AECOPD痰热壅肺证患者随机分为对照组和观察组各45例。2组均根据病情采取现代医学综合治疗措施,包括控制性氧疗、支气管扩张剂、糖皮质激素、抗菌药物等治疗措施。观察组加用中药穴位贴敷。2组疗程均为10天。治疗前后评定2组患者的慢性阻塞性肺疾病患者自我评估测试问卷(CAT)和主要症状评分;进行肺功能检查,记录治疗前后2组患者的第1秒用力呼气容积(FEV1)和第1秒用力呼气容积占预计值百分比(FEV1%);出院时评价对护理工作的满意度。结果:治疗后,2组CAT评分均较治疗前下降(P<0.01),FEV1和FEV1%均较治疗前上升(P<0.01)。观察组CAT评分低于对照组(P<0.01),FEV1和FEV1%均高于对照组(P<0.01)。2组咳嗽、痰量、喘促、呼吸困难和肺部啰音评分均较治疗前下降(P<0.01),观察组上述5项症状评分均低于对照组(P<0.01)。观察组护理满意度高于对照组(P<0.05)。结论:在常规现代医学综合疗法基础上加用中药穴位贴敷,可有效减轻AECOPD患者的临床症状,改善肺功能,提高患者的护理满意度。

Objective:To observe the clinical effect of point application with Chinese herbal medicine for acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:A total of 90 cases of AECOPD patients with phlegm-heat obstructing the lung syndrome were randomly divided into the control group and the observation group,45 cases in each group.According to the condition in each group,both groups were given comprehensive treatment of modern medicine,including controlled oxygen therapy,bronchodilator,glucocorticoid,antibiotics and other treatment measures;the observation group was additionally treated with point application with Chinese herbal medicine.Both groups were treated for10 days.Before and after treatment,the scores of COPD Assessment Test(CAT) and main symptoms in the two groups were evaluated.The pulmonary function test was performed,and the forced expiratory volume in one second(FEV1) and the percentage of predicted value of FEV1(FEV1%) before and after treatment in the two groups were recorded.The nursing satisfaction was evaluated at discharge.Results:After treatment,the scores of CAT in the two groups were decreased when compared with those before treatment(P <0.01),while the levels of FEV1 and FEV1% were increased when compared with those before treatment(P <0.01).The score of CAT in the observation group was lower than that in the control group(P <0.01),while the levels of FEV1 and FEV1 % were higher than those in the control group(P <0.01).The scores of cough,sputum volume,tachypnea,dyspnea and rales in the lung in the two groups were decreased when compared with those before treatment(P <0.01),and the scores of above five symptoms in the observation group were lower than those in the control group(P <0.01).The nursing satisfaction in the observation group was higher than that in the control group(P <0.05).Conclusion:The additional application of point application with Chinese herbal medicine based on comprehensive treatment of modern medicine can significantly alleviate the clinical symptoms of AECOPD patients,and improve their lung function as well as nursing satisfaction.