摘要
目的:考察甘草的提取方法,优选甘草中甘草酸的最佳提取工艺。方法:以甘草酸的含量为指标,对不同提取方法进行筛选;以提取溶剂、浓度和提取时间为考察因素,采用正交试验L9(3^4)优选甘草酸的最佳提取工艺。结果:最佳提取方法为超声提取法;最佳提取工艺为50%乙醇超声30 min。结论:超声提取甘草酸含量高,且该工艺简便可行,易于实现工业化提取。
Objective:To research the extraction method and select optimum extraction process of glycyrrhizic acid from Radix Glycyrrhizae.Method:The content of glycyrrhizic acid was used as the index to screen the different extraction methods.The optimum extraction process of glycyrrhizic acid was optimized by orthogonal test L9(3^4)with extraction solvent,concentration and extraction time as factors.The best extraction method was ultrasonic extraction.The optimal extraction process was 50%ethanol ultrasound for 30 min.Ultrasonic extraction of glycyrrhizic acid content was high,and the process was simple and feasible,easy to achieve industrial extraction.
作者
李越峰
辛二旦
司昕蕾
边甜甜
曹瑞
刘岩峥
LI Yuefeng;XIN Erdan;SI Xinlei;BIAN Tiantian;CAO Rui;LIU Yanzheng(University of Traditional Chinese Medicine of GanSu,Lanzhou Gansu 730000,China;key laboratory of standard and quality of Chinese medicine research of Gansu Lanzhou 730000,China;Gansu Provincial Cancer Hospital,Lanzhou Gansu 730050,China)
出处
《中兽医医药杂志》
2019年第6期44-47,共4页
Journal of Traditional Chinese Veterinary Medicine
基金
重点研发计划-社会发展类(1204FKCA140)
国家自然科学基金资助项目(81460611)
国家教育部科学技术研究重点基金资助项目(212186)
甘肃省自然科学基金资助项目(2010:1010RJZA212
2014:145 RJZA076)
甘肃省财政厅高校基本科研业务费专项基金资金项目(2013-2)
兰州市科技局项目(2014-1-188)
甘肃省中医药管理局科研课题(GZK-2015-57)
关键词
甘草
甘草酸
正交试验
提取工艺
Radix Glycyrrhizae
glycyrrhizic acid
orthogonal test
extraction process
