2016-2018年浙江省临海市8~10岁儿童尿碘水平调查

Investigation of urinary iodine levels of 8 to 10 years old children in Linhai City of Zhejiang Province from 2016 to 2018

目的了解临海市8~10岁儿童碘营养状况,为碘缺乏病防治工作提供理论依据.方法2016-2018年,在临海市所辖的乡镇、街道办事处,按东、西、南、北、中5个方位各抽取1个乡镇(街道),每个乡镇(街道)选取1所中心小学,每所小学抽取40名8~10岁儿童,采集儿童中段尿5~10 ml,尿碘检测采用砷铈催化分光光度法.结果共检测儿童尿样620份,尿碘中位数为172.5μg/L.其中,2016年检测200份,儿童尿碘中位数为191.5μg/L,<100μg/L的占14.00%(28/200),≥300μg/L的占20.00%(40/200);2017年检测210份,儿童尿碘中位数为174.5μg/L,<100μg/L的占18.10%(38/210),≥300μg/L的占11.90%(25/210);2018年检测210份,儿童尿碘中位数为149.0μg/L,<100μg/L的占24.29%(51/210),≥300μg/L的占9.05%(19/210).不同年份儿童尿碘含量比较差异有统计学意义(H=20.831,P<0.05).共检测男童尿样310份,尿碘中位数为147.5μg/L;女童尿样310份,尿碘中位数为119.5μg/L,不同性别儿童尿碘含量比较差异有统计学意义(Z=2.766,P<0.05).结论临海市8~10岁儿童碘营养水平在适宜范围(100~199μg/L)内,但仍要继续做好尿碘的监测工作.

Objective To investigate the iodine nutritional status of 8 to 10 years old school children in Linhai City,and to provide a theoretical basis for prevention and treatment of iodine deficiency.Methods From 2016 to 2018,in the townships and sub-district offices under the jurisdiction of Linhai City,one town(street)was selected according to its geographical distribution in the east,west,south,north,and middle five directions,and one central primary school was selected in each town(street).In each central primary school,40 children aged 8 to 10 years were selected,5 to 10 ml of urine samples were collected,and urinary iodine level was determined by arsenic cerium catalytic spectrophotometry.Results A total of 620 urine samples were detected in children,and the median urinary iodine was 172.5μg/L.In 2016,200 samples were tested,the median urinary iodine was 191.5μg/L,14.00%(28/200)for<100μg/L,and 20.00%(40/200)for≥300μg/L;in 2017,210 samples were tested,the median urinary iodine was 174.5μg/L,18.10%(38/210)for<100μg/L,11.90%(25/210)for≥300μg/L;in 2018,210 samples were tested,the median urinary iodine was 149.0μg/L,24.29%(51/210)for<100μg/L,and 9.05%(19/210)for≥300μg/L.The differences in urinary iodine concentration between the three years were statistically significant(H=20.831,P<0.05).A total of 310 boys were tested urinary iodine level,with a median of 147.5μg/L,and 310 girls were tested with a median of 119.5μg/L.The difference in urinary iodine concentration between boys and girls was statistically significant(Z=2.766,P<0.05).Conclusion The iodine nutritional level of 8 to 10 years old school children in Linhai City is within the appropriate range(100-199μg/L),but the monitoring of urinary iodine should continue.