注射用胰蛋白酶配合手术治疗股骨粗隆骨折临床研究

Clinical Study of Injection of Trypsin Combined with Surgery for Femoral Trochanteric Fracture

目的探讨注射用胰蛋白酶配合手术治疗股骨粗隆骨折的临床疗效。方法方便选取2018年10月—2019年3月期间该院收治的98例股骨粗隆骨折患者,随机分为对照组和观察组,各49例。对照组患者根据股骨粗隆骨折情况采取手术治疗,观察组在对照组基础上增加创面注射用胰蛋白酶稀释液喷洒治疗,对比两组患者术后髋关节功能恢复效果,同时对比两组康复效率及术后并发症情况。结果观察组术后住院时间(12.36±5.03)d和术后下地负重行走时间(10.25±4.03)d显著低于对照组(15.25±3.05)d、(14.05±3.96)d,差异有统计学意义(t=10.547,12.358,P<0.05)。观察组髋关节功能优良率(93.88%)显著高于对照组(79.59%),差异有统计学意义(χ2=4.392,P=0.023)。观察组和对照组比较,术后并发症发生率(4.08%vs 18.37%)差异有统计学意义(χ2=3.387,P=0.029)。结论注射用胰蛋白酶配合手术治疗股骨粗隆骨折疗效可靠,康复效率显著提升,并发症风险显著降低,预后良好,应用价值较高。

Objective To investigate the clinical efficacy of injection of trypsin combined with surgery for the treatment of femoral trochanteric fractures.Methods convenient selected ninety-eight patients with femoral trochanteric fractures admitted to the hospital from October 2018 to March 2019 were randomLy divided into control group and observation group,with 49 cases in each group.The patients in the control group underwent surgical treatment according to the femoral trochanteric fracture.The observation group increased the wound injection with trypsin dilution on the basis of the control group,compared the recovery effect of the hip joint function between the two groups,and compared the rehabilitation efficiency,postoperative complications of the two groups.Results The postoperative hospital stay(12.36±5.03)d and the postoperative weight walking time(10.25±4.03)d were significantly lower in the observation group than in the control group(15.25±3.05d,14.05±3.96d).The difference was statistically significant(t=10.547,12.358,P<0.05).The excellent rate of hip function in the observation group(93.88%)was significantly higher than that in the control group(79.59%),and the difference was statistically significant(χ2=4.392,P=0.023).The incidence of postoperative complications(4.08%vs 18.37%)was statistically significant between the observation group and the control group,the difference was statistically significant(χ2=3.387,P=0.029).Conclusion The injection of trypsin combined with surgery for the treatment of femoral trochanteric fractures is reliable,the rehabilitation efficiency is significantly improved,the risk of complications is significantly reduced,the prognosis is good,and the application value is high.