负压封闭引流术联合抗生素骨水泥治疗创伤性骨髓炎的效果分析

Negative Pressure Sealing Drainage Combined with Antibiotic Bone Cement in the Treatment of Traumatic Osteomyelitis

目的探究将负压引流术联合抗生素骨水泥应用于治疗创伤性骨髓炎患者中的效果评价及临床应用意义。方法在该院数据库中调取时间段2016年8月—2018年12月间收入的所有创伤性骨髓炎患者的一般资料,根据实验要求纳入其中64例患者作为该次研究实验样本,通过随机分组法将所有患者进行两组。均分分别记录为对照组与实验组、每组中录入32例患者。对照组患者单纯应用抗生素骨水泥进行治疗,实验组患者则在此基础上加用负压引流技术进行治疗,记录所有患者治疗完成后的住院天数、手术时间、创面愈合时间以及复发率等临床指标,评价两种手术方案的差异。结果治疗完成后实验组患者的住院天数、手术平均时间以及手术次数与对照组相比,差异无统计学意义(t=0.253,P=0.801;t=0.211,P=0.230;t=1.942,P=0.057)。而实验组患者的创面愈合时间、换药次数较对照组来说明显更少,数据对比分析差异有统计学意义(t=5.122,P=0.000;t=10.808,P=0.000)。实验组患者的复发率为3.13%(1/32),对照组患者的复发率为25.00%(8/32),数据对比分析差异有统计学意义(χ2=19.786,P=0.000)。结论在对创伤性骨髓炎患者进行治疗时,应用负压引流技术,联合抗生素骨水泥进行治疗,能够取得较好的治疗效果,缩短患者的创面愈合时间,减少换药次数,对于降低患者的复发率来说有积极意义,是一种安全且有效的手术方案,值得推广使用。

Objective To explore the effect evaluation and clinical significance of negative pressure drainage combined with antibiotic bone cement in the treatment of traumatic osteomyelitis.Methods General data of all patients with traumatic osteomyelitis were collected in the hospital database from August 2016 to December 2018.According to the requirements of the experiment,64 patients were included as the experimental samples in this study.All patients were divided into two groups by random grouping method.The average score was recorded as 32 patients in each group of the control group and the experimental group.Patients in the control group were treated with antibiotic bone cement alone,while patients in the experimental group were treated with negative pressure drainage.The differences between the two surgical schemes were evaluated by clinical indicators such as hospitalization days,operation time,wound healing time and recurrence rate.Results There was no statistically significant difference in hospitalization days,average operation time and number of operations between the experimental group and the control group(t=0.253,P=0.801;t=0.211,P=0.230;t=1.942,P=0.057).The wound healing time and dressing change times of the experimental group were significantly less than those of the control group,and the difference were statistically significantly different(t=5.122,P=0.000;t=10.808,P=0.000).The recurrence rate of the experimental group was 3.13%(1/32)and that of the control group was 25.00%(8/32).There was a statistically significant difference between the two groups(χ2=19.786,P=0.000).Conclusion When treating traumatic osteomyelitis patients,negative pressure drainage combined with antibiotic bone cement can achieve better therapeutic effect,shorten the wound healing time and reduce the number of dressing changes.It has positive significance for reducing the recurrence rate of patients, and is a safe and effective surgical program worthy of popularization.