高危剖宫产孕妇产后出血中应用欣母沛防治的疗效探讨

Therapeutic Effect of Hemabate in the Treatment of Postpartum Hemorrhage in High-risk Cesarean Section

目的探讨应用欣母沛在高危剖宫产孕妇产后出血中的疗效。方法研究对象为方便选取2017年2月—2018年2月在该院接受剖宫产的80例高危孕妇,采取随机数字表法将其分为对照组与研究组,每组40例。对照组给予缩宫素对孕妇产后出血进行预防,同时联合应用卡孕栓直肠给药。研究组给予欣母沛对孕妇产后出血进行预防,对两组孕妇的产后出血量、术中术后输血、宫纱条及球囊使用、术后子宫恢复等临床指标进行对比分析。结果产后出血量对比:研究组孕妇术中出血量为﹙102.33±19.98﹚mL、产后2 h出血量为﹙207.62±65.14﹚mL、产后24 h出血量为﹙40.45±32.64﹚mL;对照组孕妇术中出血量为﹙234.15±26.43﹚mL、产后2 h出血量为﹙321.09±80.42﹚mL、产后24 h出血量为﹙84.12±50.07﹚mL;研究组孕妇术中出血量、产后2 h出血量以及产后24 h出血量均显著低于对照组(t=43.258、10.369、7.011,P=0.001、0.002、0.001)。研究组术中术后输血、宫纱条使用、球囊使用、术后子宫恢复等各项临床指标均明显优于对照组(χ2=4.682、4.756、4.633、8.641,P=0.019、0.024、0.027、0.033)。结论高危剖宫产孕妇应用欣母沛可对产后出血起到良好的防治作用,值得临床加大研究并推广采用。

ObjectiveTo explore the efficacy of hemabate in the postpartum hemorrhage of high-risk cesarean section pregnant women.Methods The study subjects were 80 high-risk pregnant women who underwent cesarean section in our hospital from February 2017 to February 2018.They were convenient selection randomly divided into a control group and a study group,40 cases each group.The control group was given oxytocin to prevent postpartum hemorrhage in pregnant women,and combined with rectal administration.The research group gave hemabate prevention of postpartum hemorrhage in pregnant women.The clinical indexes of postpartum hemorrhage,intraoperative blood transfusion,intrauterine strip and balloon use,and postoperative uterine recovery were compared.Results Comparison of postpartum hemorrhage:the intraoperative blood loss of the pregnant women in the study group was﹙102.33±19.98﹚mL,the bleeding volume at 20 h postpartum was﹙207.62±65.14﹚mL,and the bleeding volume at 24 h postpartum was﹙40.45±32.64﹚mL.The intraoperative blood loss of the control group was﹙234.15±26.43﹚mL,2 h postpartum hemorrhage.The amount of blood was﹙32.1±09±80.42﹚mL,and the amount of bleeding was﹙84.12±50.07﹚mLafter birth.The amount of intraoperative blood loss,postpartum hemorrhage and postpartum 24 bleeding in the study group were significantly lower than those in the control group(t=43.258,10.369,7.011,P=0.001,0.002,0.001).The blood transfusion and uterine strips were used in the study group.The clinical indexes of balloon use and postoperative uterine recovery were significantly better than the control group(χ2=4.682,4.756,4.633,8.641,P=0.019,0.024,0.027,0.033).ConclusionHigh-risk cesarean section pregnant women with hemabate can play a good role in prevention and treatment of postpartum hemorrhage,it is worthy of clinical research and promotion.