Genes&Diseases 2018年封面文章集锦

(2019年9月被SCIE收录)www.joumals.elsevier.com/genes-and-diseasesEpigenetics,first coined by Conrad Waddington in 1942,is currently defined as the study of heritable changes in gene expression that do not involve alteration of the DNA sequence itself.The word"epigenetic"literally means"in addition to,above,or on top of the changes in genetic coding sequence or genomic DNA.^,The term"epigenetics",or a more proper term"epigenomics",has evolved to include any process that alters gene activity without changing DNA sequence and the modifications that can be transmitted to progeny cells.