摘要
目的:运用正交试验设计优化泽兰多糖的超声提取工艺,为泽兰多糖的开发提供理论基础。方法:以泽兰多糖提取率、多糖含量为双重指标,考察温度、时间、料液比、功率对提取结果的影响,通过正交实验设计来优选超声提取泽兰多糖的工艺参数。结果:优选的泽兰多糖的超声提取工艺为:超声功率为560W,温度60℃,时间20 min,料液比为30倍,多糖提取率可以达到2.31%。结论:本研究得到的泽兰多糖超声提取工艺科学稳定,具有先进性,值得进一步推广应用。
Objective:The aim of this study was to optimizate the ultrasonic extraction process of polysaccharides from Lycopus lucidus based on orthogonal experiments design.Methods:The extraction rate of polysaccharide from Lycopus lucidus was used as the index,we investigated the influencing factors of ultrasonic extraction(temperature,time,solid-liquid ratio and ultrasonic power),and then determined the optimal extracting technology by orthogonal experiment.Results:The optimal ultrasonic extracting technology as follows:ultrasonic power was 560 W.The temperature was 60℃and the time was 20 min.The solid-liquid ratio was 30 times.The extraction rate of polysaccharide can reach 2.31%.Conclusion:The ultrasonic extraction process is a stable technology obtained from this experiment,and has a higher progressiveness,worthy of further development.
作者
刘蕾
冯素香
刘富岗
刘炯
LIU Lei;FENG Suxiang;LIU Fugang;LIU Jiong(Pharmacy Department’Children’s Hospital Affiliated to Zhengzhou University,Zhengzhou 450053,Henan,China;Pharmacy Department,Henan Children’s Hospital,Zhengzhou 450053,Henan,China;Pharmacy Department,Zhengzhou Children's Hospital,Zhengzhou 450053,Henan,China;Pharmacy College,Henan University of Traditional Chinese Medicine,Zhengzhou 450046,Henan,China;Collaborative Innovation Center for Respiratory Diseases Diagnosis and Chinese Medicine Development of Henan Province,Zhengzhou 450046,Henan,China;Henan Key Laboratory of Chinese Medicine for Respiratory Disease,Zhengzhou 450046,Henan,China)
出处
《辽宁中医杂志》
CAS
2019年第11期2378-2381,共4页
Liaoning Journal of Traditional Chinese Medicine
基金
国家自然科学基金面上项目(81603556)
关键词
正交试验
泽兰
多糖
超声提取
双重指标
orthogonal experiments design
Lycopus lucidus
polysaccharides
ultrasonic extraction
double index