期刊文献+

左乙拉西坦添加治疗儿童难治性癫痫部分性发作的研究 被引量:5

下载PDF
导出
摘要 目的:观察左乙拉西坦添加治疗儿童难治性癫痫部分性发作的疗效,以及对不同发作类型、不同用药情况下的治疗效果和用药安全性。方法:对57例儿童难治性癫痫部分性发作添加左乙拉西坦治疗,观察其治疗效果。结果:左乙拉西坦治疗儿童难治性癫痫部分性发作,总有效率为70%。结论:左乙拉西坦治疗儿童难治性癫痫效果良好,不良反应少。
出处 《癫痫与神经电生理学杂志》 2019年第6期358-360,共3页 Journal of Epileptology and Electroneurophysiology(China)
  • 相关文献

参考文献4

二级参考文献27

  • 1吴洵昳,洪震,吴逊,吴立文,赵忠新,王学峰,周东,吕传真.多中心双盲、随机、安慰剂对照评价左乙拉西坦添加治疗难治性部分性癫癎发作的疗效及安全性[J].中华神经科杂志,2007,40(3):149-153. 被引量:44
  • 2丁庆明,任连坤.抗癫痫新药左乙拉西坦的临床应用和安全性[J].药物不良反应杂志,2007,9(4):295-301. 被引量:39
  • 3Labate A, Colosimo E, Gambardella A,et al. Levetiracetam in patients with generalized epilepsy andmyoclonic seizures: an open label study. Seizure,2006,15(3) :214-218.
  • 4Kaminski RM, Matagne A, Patsalos PN, et al. Benefit of combina- tion therapy in epilepsy:a review of the preclinical evidence with levetiracetam. Epilepsia, 2009,50(3) : 387-397.
  • 5Steinhof B J, Trink E, Wieser HG. Levetiracetam in patients with refractory epilepsy: results of the SKATE trial in Austria, Ger- many and Switzerland. Seizure,2005,14(7):490-496.
  • 6Rafal MK,Michel G,Karine L,et al. Proepileptic phenotype of SV2A-deficient mice is associated with reduced anticonvulsant ef-ficacy of levetiracetam. Epilepsia,2009,50(7) : 1729-1740.
  • 7Patsalos PN. Pharmacokinetic profile of levetiracetam: toward ideal characteristics. Pharmacol Ther, 2000,85 : 77-85.
  • 8Grosso S, Cordelli D, Franzoni E, et al. Efficacy and safety of lev- etiracetam in infants and young children with refractory epilepsy. Seizure, 2007,16(4) : 345-350.
  • 9Opp J,Tuxhorn I,May T,et al. Levetiracetam in children with re- fractory epilepsy:a multicenter open label study in Germany. Seizure, 2005,14(7) :476-484.
  • 10Wu T,Chen CC,Chen TC,et al. Clinical efficacy and cognitive and neuropsychological effects of levetiracetam in epilepsy: an open-label multicenter study. Epilepsy Behav, 2009,16 (3) : 468- 474.

共引文献88

同被引文献42

引证文献5

二级引证文献129

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部